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Topical ophthalmic cyclosporine in the treatment of toxic epidermal necrolysis     
Yazarlar
Zafer Onaran
Kırıkkale Üniversitesi, Türkiye
Usta Gülşah
Koçak Mukadder
Prof. Dr. Kemal ÖRNEK
Kırıkkale Üniversitesi, Türkiye
Ünase Büyükkoçak
Yüksek İhtisas Üniversitesi, Türkiye
Özet
Aim. To describe a case of toxic epidermal necrolysis (TEN) with ocular involvement treated with topical ophthalmic cyclosporine. Case Presentation. A 20-year-old woman developed TEN following administration of carbamazepine that was prescribed for epilepsy. Ophthalmic examination revealed bilateral pseudomembranous conjunctivitis. She was hospitalized in the intensive care unit and treated with intravenous corticosteroid and immunoglobulin. Topical cyclosporine was used in combination with topical corticosteroids for ocular surface disease. Following two months of ocular treatment, she recovered without any severe ocular complication. Ocular examination at the four-month followup showed a 2mm of symblepharon in the lower fornix as the sole pathologic finding. Conclusion. Topical ophthalmic cyclosporine may contribute to decrease the ophthalmic complications of TEN and should be considered in the acute stage of the disease.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü Uluslararası alan indekslerindeki dergilerde yayımlanan tam makale
Dergi Adı Case Rep Med.
Dergi Tarandığı Indeksler HINARI
Makale Dili İngilizce
Basım Tarihi 01-2011
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 4
Google Scholar 7

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