Topical ophthalmic cyclosporine in the treatment of toxic epidermal necrolysis
   
Yazarlar (5)
Zafer Onaran Kirikkale Üniversitesi, Türkiye
Gülşah Usta Kirikkale Üniversitesi, Türkiye
Mukadder Koçak
Kirikkale Üniversitesi, Türkiye
Prof. Dr. Kemal ÖRNEK Kirikkale Üniversitesi, Türkiye
Ünase Büyükkoçak Kirikkale Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale)
Dergi Adı Case Reports in Medicine
Dergi ISSN 1687-9627 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler HINARI
Makale Dili İngilizce Basım Tarihi 01-2011
Cilt / Sayı / Sayfa 2011 / 1 / 416842–0 DOI 10.1155/2011/416842
Makale Linki https://downloads.hindawi.com/journals/crim/2011/416842.pdf
Özet
Aim. To describe a case of toxic epidermal necrolysis (TEN) with ocular involvement treated with topical ophthalmic cyclosporine. Case Presentation. A 20‐year‐old woman developed TEN following administration of carbamazepine that was prescribed for epilepsy. Ophthalmic examination revealed bilateral pseudomembranous conjunctivitis. She was hospitalized in the intensive care unit and treated with intravenous corticosteroid and immunoglobulin. Topical cyclosporine was used in combination with topical corticosteroids for ocular surface disease. Following two months of ocular treatment, she recovered without any severe ocular complication. Ocular examination at the four‐month followup showed a 2 mm of symblepharon in the lower fornix as the sole pathologic finding. Conclusion. Topical ophthalmic cyclosporine may contribute to decrease the ophthalmic complications of TEN and should be considered …
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