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PARTS FROM LIFE-CYCLE OF H.ERINACEUS: RESPONSE SURFACE METHODOLOGY APPROACH TO OPTIMIZE EXTRACTION CONDITIONS AND DETERMINATION OF ITS ANTIOXIDANT, ANTIDIABETIC AND NTIMICROBIAL EFFECT    
Yazarlar (3)
Nurcan Doğan
Türkiye
Cemhan Doğan
Türkiye
Funda Atila
Kırşehir Ahi Evran Üniversitesi, Türkiye
Devamını Göster
Özet
In this article, optimization of extraction conditions of different parts from the life cycle of H.erinaceus was investigated based on Response Surface Method. Furthermore, antioxidant, antidiabetic, and antimicrobial effects of optimized extracts were studied. Results: Temperature, liquid / solid ratio, and solvent concentration significantly affected the phenolic content and antioxidant capacities of all samples. The young fruit body of H.erinaceus had higher antioxidant (43.11 +/- 2.74, 51.39 +/- 2.34, 62.84 +/- 1.59 mu mol TE/g for DPPH, FRAP and ABTS, respectively) and antidiabetic effects (93.54 +/- 2.3 and 132.25 +/- 1.38 mu g/mL for IC50 values of alpha-glucosidase and alpha-amylase, respectively) than mycelium. However, these effects partially decrease as the fruit body ages. Besides, the optimized extracts exhibited more antimicrobial effects on Gram-positive bacteria than Gram-negative bacteria. Conclusion: Both the fruit body and the mycelium of H. erinaceus have many bio-functional properties. However, these properties of the fruit body decrease significantly with the delay of the harvest time. The extraction process conditions we optimize in this study can be adapted to large-scale separation processes in the industry.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü ESCI dergilerinde yayımlanan tam makale
Dergi Adı Journal of Microbiology, Biotechnology and Food Sciences
Dergi ISSN 1338-5178
Dergi Tarandığı Indeksler Emerging Sources Citation Index (ESCI)
Makale Dili Türkçe
Basım Tarihi 01-2021
Cilt No 10
Doi Numarası 10.15414/jmbfs.3703
Makale Linki http://dx.doi.org/10.15414/jmbfs.3703