Is choroidal thickness related with disease activity and joint damage in patient with rheumatoid arthritis
      
Yazarlar (6)
A. Kurt
Kırşehir Ahi Evran Üniversitesi, Türkiye
E. E. Kurt
Kırşehir Ahi Evran Üniversitesi, Türkiye
R. Kilic
Kırşehir Ahi Evran Üniversitesi, Türkiye
C. Oktem
Kırşehir Ahi Evran Üniversitesi, Türkiye
Prof. Dr. Figen TUNCAY Kırşehir Ahi Evran Üniversitesi, Türkiye
H. R. Erdem
Kırşehir Ahi Evran Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Bratislava Medical Journal
Dergi ISSN 0006-9248 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2017
Cilt / Sayı / Sayfa 118 / 1 / 23–27 DOI 10.4149/BLL_2017_005
Makale Linki http://www.elis.sk/index.php?page=shop.product_detailsflypage=flypage.tplproduct_id=5082category_id=135option=com_virtuemart
Özet
OBJECTIVE: Aim of the study was to evaluate the choroidal thickness (CT) in patients with RA and detect the relation with disease activity and joint damage in patients with rheumatoid arthritis
BACKGROUND: Rheumatoid arthritis (RA) is a systemic inflammatory disease associated with various extra articular organ manifestations including ocular manifestations
MATERIALS AND METHODS: We included 59 eyes of 59 patients with RA and 59 eyes of 59 controls without RA in the study. Subfoveal and perifoveal CT were measured using enhanced depth imaging optic coherence tomography. Disease activity score 28 (DAS 28) and Larsen score were calculated for each patient with RA and compared with measurements of CT.
RESULTS: CT was statistically thinner in patients with RA than controls, at subfoveal CT (p = 0.008), at 500 pm temporal to the fovea (p = 0.004), at 1000 mu m temporal to the fovea (p = 0.010), at 1500 pm temporal to the fovea (p = 0.005), at 500 mu m nasal to the fovea (p = 0.035). Additionally there was no correlation measurements of CT with disease activity and joint damage.
CONCLUSIONS: Subfoveal and perifoveal CT was significantly thinner in patients with RA than in healthy controls but there was no correlation detected between CT measurements and DAS 28 or Larsen scores (Tab. 5, Ref. 33). Text in PDF www.elis.sk.
Anahtar Kelimeler
Choroidal thickness, rheumatoid arthritis, joint damage, disease activity, optical coherence tomography