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Is choroidal thickness related with disease activity and joint damage in patient with rheumatoid arthritis       
Yazarlar
Ali Kurt
Kırşehir Ahi Evran Üniversitesi, Türkiye
Emine Eda Kurt
Kırşehir Ahi Evran Üniversitesi, Türkiye
Raşit Kılıç
Kırşehir Ahi Evran Üniversitesi, Türkiye
Çağlar Öktem
Prof. Dr. Figen TUNCAY Prof. Dr. Figen TUNCAY
Kırşehir Ahi Evran Üniversitesi, Türkiye
Hatice Rana Erdem
Kırşehir Ahi Evran Üniversitesi, Türkiye
Özet
OBJECTIVE: Aim of the study was to evaluate the choroidal thickness (CT) in patients with RA and detect the relation with disease activity and joint damage in patients with rheumatoid arthritis
BACKGROUND: Rheumatoid arthritis (RA) is a systemic inflammatory disease associated with various extra articular organ manifestations including ocular manifestations
MATERIALS AND METHODS: We included 59 eyes of 59 patients with RA and 59 eyes of 59 controls without RA in the study. Subfoveal and perifoveal CT were measured using enhanced depth imaging optic coherence tomography. Disease activity score 28 (DAS 28) and Larsen score were calculated for each patient with RA and compared with measurements of CT.
RESULTS: CT was statistically thinner in patients with RA than controls, at subfoveal CT (p = 0.008), at 500 pm temporal to the fovea (p = 0.004), at 1000 mu m temporal to the fovea (p = 0.010), at 1500 pm temporal to the fovea (p = 0.005), at 500 mu m nasal to the fovea (p = 0.035). Additionally there was no correlation measurements of CT with disease activity and joint damage.
CONCLUSIONS: Subfoveal and perifoveal CT was significantly thinner in patients with RA than in healthy controls but there was no correlation detected between CT measurements and DAS 28 or Larsen scores (Tab. 5, Ref. 33). Text in PDF www.elis.sk.
Anahtar Kelimeler
Choroidal thickness, rheumatoid arthritis, joint damage, disease activity, optical coherence tomography
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Bratislava Medical Journal
Dergi ISSN 1336-0345
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 01-2017
Cilt No 118
Sayı 1
Sayfalar 23 / 27
Doi Numarası 10.4149/BLL_2017_005
Makale Linki http://www.elis.sk/index.php?page=shop.product_detailsflypage=flypage.tplproduct_id=5082category_id=135option=com_virtuemart