In silico detection of Cucurbitacin-E on antioxidant enzymes of model organism Galleria mellonella L. (Lepidoptera: Pyralidae) and variation of antioxidant enzyme activities and lipid peroxidation in treated larvae
Yazarlar (3)
Prof. Dr. Fahriye ERCAN Kırşehir Ahi Evran Üniversitesi, Türkiye
Hatice Baş Bozok Üniversitesi, Türkiye
Prof. Dr. Serap YALÇIN AZARKAN Kırşehir Ahi Evran Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(ESCI dergilerinde yayınlanan tam makale)
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| Dergi Adı | Beni Suef University Journal of Basic and Applied Sciences | ||
| Dergi ISSN | 2314-8535 | ||
| Dergi Tarandığı Indeksler | Emerging Sources Citation Index, Zoological Record | ||
| Makale Dili | Türkçe | Basım Tarihi | 10-2022 |
| Cilt / Sayı / Sayfa | 11 / 1 / 130–0 | DOI | 10.1186/s43088-022-00310-3 |
| Makale Linki | https://bjbas.springeropen.com/counter/pdf/10.1186/s43088-022-00310-3 | ||
| Özet |
| BackgroundIn silico studies further provided predictive binding properties of selected ligands for inhibition of target protein. In the study, molecular binding poses of Cucurbitacin-E and antioxidant enzymes (glutathione-S-transferase (GST), superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR), glutathione peroxidase (GPx) and acetylcholinesterase (AChE) of Galleria mellonella were determined in silico. Cucurbitacins are the most important components of Ecballium elaterium. The first cucurbitacin isolated from the plant was Cucurbitacin-E. In this study, the toxic effect of E. elaterium (L.) A. Rich. (Cucurbitaceae) fruit juice on G. mellonella (Lepidoptera: Pyralidae) larvae, which is known as a good model insect, was also detected, and its effect on antioxidant enzyme activities and lipid peroxidation was revealed.ResultsThe plant fruit juice was tested on the target larvae of G. mellonella with … |
| Anahtar Kelimeler |
| Antioxidant enzyme | Ecballium elaterium | Galleria mellonella | Pest control |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 14 |
| SCOPUS | 14 |
| Google Scholar | 16 |