The Relationship Between Serum Endocan Level and Aortic Elastic Properties in Patients With Newly Diagnosed Essential Hypertension
 
Yazarlar (6)
Mustafa Çelik Kırşehir Ahi Evran Üniversitesi, Türkiye
Prof. Dr. Erdoğan SÖKMEN Kırşehir Ahi Evran Üniversitesi, Türkiye
Serkan Sivri
Kirsehir Ahi Evran University
Cahit Uçar Kırşehir Ahi Evran Üniversitesi, Türkiye
Rukiye Nar
Pamukkale Üniversitesi, Türkiye
Murat Erer
Kırşehir Ahi Evran Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı ANGIOLOGY (Q3)
Dergi ISSN 0003-3197 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce Basım Tarihi 08-2019
Cilt / Sayı / Sayfa 70 / 7 / 662–668 DOI 10.1177/0003319718823625
Makale Linki http://journals.sagepub.com/doi/10.1177/0003319718823625
Özet
Endothelial dysfunction plays role in the generation of both essential hypertension (EH) and aortic stiffness. We evaluated the relationship between serum endocan level and aortic elastic properties (AEPs) assessed with the aortic strain, aortic distensibility, and aortic stiffness index by echocardiography. Newly diagnosed EH patients (n = 67) and controls (n = 70) were included in the study. The EH group was subdivided into stage 1 and 2 EH groups. A higher endocan level was found in the EH group, compared to the controls (34.2 ± 13.0 vs 24.1 ± 7.3 ng/mL, respectively, P < .001). All the AEP parameters were worse in the EH group, compared to the controls. Further, endocan levels correlated with aortic distensibility (r = −0.305, P < .001) and aortic strain (r = −0.181, P = .038), but not with aortic stiffness index (r = 0.162, P = .064) in the whole study population. Aortic elastic properties deteriorate and serum …
Anahtar Kelimeler
serum endocan level | aortic stiffness | essential hypertension