| Yazarlar |
Doç. Dr. Erdoğan SÖKMEN
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Sinan Cemgil Özbek
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Mustafa Çelik
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Serkan Sivri
|
|
Mehmet Metin
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Mustafa Avcu
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| BackgroundVentricular arrhythmias are reported to be more common in patients with obstructive sleep apnea (OSA). Preliminary evidence showed such parameters regarding ventricular repolarization as Tp-e, Tp-e/QT, and Tp-e/QTc may be related with increased cardiac arrhythmias and even sudden cardiac death. The purpose of the present study was to evaluate ventricular repolarization during immediately preapnea period, apnea period, and postapnea hyperventilation period in patients with OSA. MethodsA total of 59 patients who underwent polysomnography and were diagnosed with OSA between the years 2016-2017 in our hospital were included in our study. Of 59 patients (mean age: 52.519.66), 28 were male and 31 were female. In all patients, Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio, together with some other parameters, were calculated. Categorical variables were expressed as proportion and continuous variables were expressed as meanstandard deviation. Electrocardiogram calculations of interest were compared through preapnea, apnea, and postapnea periods using Friedman's test. ResultsTp-e interval (85.6ms [78.3-95.6], 98ms [88.5-107.7], 91.2ms [81-98.8], respectively; P<0.001), Tp-e/QT ratio (0.219 [0.202-0.237], 0.242 [0.224-0.269], 0.233 [0.212-0.246], respectively; P<0.001), and Tp-e/QTc ratio (0.210 [0.190-0.222], 0.233 [0.209-0.247], 0.212 [0.193-0.229], respectively; P<0.001) were significantly increased during apnea period compared to the preapnea period and significantly decreased during postapnea hyperventilation period compared to the apnea period. ConclusionTp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio were shown to be increased during apnea period and decreased during postapnea hyperventilation period. Our findings may help explain cardiac arrhythmias and sudden death in OSA patients. |
| Anahtar Kelimeler |
| obstructive sleep apnea | parameters of ventricular repolarization | ventricular arrhythmias |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY |
| Dergi ISSN | 0147-8389 |
| Dergi Tarandığı Indeksler | SCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 07-2018 |
| Cilt No | 41 |
| Sayı | 7 |
| Sayfalar | 762 / 766 |
| Doi Numarası | 10.1111/pace.13365 |
| Makale Linki | http://doi.wiley.com/10.1111/pace.13365 |
| Atıf Sayıları | |
| WoS | 17 |
