Elevated Serum Uric Acid Predicts Angiographic Impaired Reperfusion and 1-Year Mortality in ST-Segment Elevation Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention
 
Yazarlar (14)
Nihat Şen
Gönül Erden
Selçuk Kanat
Sağlık Bilimleri Üniversitesi, Türkiye
Prof. Dr. Erdoğan SÖKMEN Kırşehir Ahi Evran Üniversitesi, Türkiye
Ahmet İşleyen
Hüseyin Yüzgeçer
Mehmet Fatih Özlü
Türkiye
Orhan Maden
Sağlık Bilimleri Üniversitesi, Türkiye
Adrıan Covıc
Rıchard J Johnson
Mehmet Kanbay Koç Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of Investigative Medicine (Q4)
Dergi ISSN 1081-5589 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce Basım Tarihi 08-2011
Kabul Tarihi 12-04-2026 Yayınlanma Tarihi
Cilt / Sayı / Sayfa 59 / 6 / 931–937 DOI 10.2310/JIM.0b013e318214ebaf
Makale Linki http://jim.bmj.com/lookup/doi/10.2310/JIM.0b013e318214ebaf
Özet
BackgroundSerum uric acid (SUA) is associated with microvascular disease that could alter coronary blood flow and prognosis. We evaluated the effects of admission SUA levels on coronary blood flow and prognosis in 185 consecutive patients with ST-segment elevation myocardial infarction (STEMI) who underwent acute primary percutaneous coronary intervention (PCI).MethodsPatients undergoing PCI for an acute STEMI were stratified into elevated SUA (>6.5 mg/dL) and normal SUA group (≤6.5 mg/dL). Primary end points were post-PCI myocardial blood flow and in-hospital and 1-year mortality.ResultsSerum uric acid level was high in 45 patients (24%) on admission. Subjects with elevated SUA had a higher prevalence of hypertension, previous myocardial infarction, multivessel disease, and Killip functional class III or higher. Corrected thrombolysis in myocardial infarction (TIMI) frame count was longer …
Anahtar Kelimeler
uric acid | ST-segment elevation myocardial infarction | mortality | primary percutaneous coronary intervention