Relationship of growth differentiation factor-15 with aortic stiffness in essential hypertension
 
Yazarlar (5)
Prof. Dr. Erdoğan SÖKMEN Kırşehir Ahi Evran Üniversitesi, Türkiye
Cahit Uçar Kırşehir Ahi Evran Üniversitesi, Türkiye
Serkan Sivri
Kirsehir Ahi Evran University
Mustafa Çelik Kırşehir Ahi Evran Üniversitesi, Türkiye
Kenan Güçlü Kirsehir Ahi Evran University
Makale Türü Açık Erişim Özgün Makale (ESCI dergilerinde yayınlanan tam makale)
Dergi Adı Future Science OA
Dergi ISSN 2056-5623 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler Emerging Sources Citation Index (Web of Science)
Makale Dili İngilizce Basım Tarihi 08-2019
Kabul Tarihi 12-04-2026 Yayınlanma Tarihi
Cilt / Sayı / Sayfa 5 / 7 / 406–0 DOI 10.2144/fsoa-2019-0029
Makale Linki https://www.future-science.com/doi/10.2144/fsoa-2019-0029
Özet
Aim: We aimed to assess the relationship between echocardiographic parameters of aortic elasticity, namely aortic strain, aortic distensibility and aortic β-index, and serum growth differentiation factor (GDF)-15 in patients with newly diagnosed essential hypertension (HT). Methods: Grade-1 HT patients (n = 50), grade-2 HT (n = 70) patients and 35 healthy controls were included. Results: GDF-15 was greater in grade-2 HT group compared with the other groups. All aortic elasticity parameters were worse in grade-2 HT group compared with the other groups. GDF-15 correlated positively with E/E′ ratio (the ratio of transmitral E velocity to mean diastolic mitral annular velocity) and β-index; and aortic strain and aortic distensibility correlated negatively with serum GDF-15. β-index, aortic diastolic diameter and diastolic blood pressure were independently associated with GDF-15. Conclusion: GDF-15 may be utilized in …
Anahtar Kelimeler
aortic elastic properties | echocardiography | GDF-15 | hypertension
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Google Scholar 16
Web of Science 6
Relationship of growth differentiation factor-15 with aortic stiffness in essential hypertension

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