Yazarlar (8) |
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![]() Kırşehir Ahi Evran Üniversitesi, Türkiye |
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![]() Selçuk Üniversitesi, Türkiye |
![]() Selçuk Üniversitesi, Türkiye |
![]() Kırşehir Ahi Evran Üniversitesi, Türkiye |
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Özet |
Aim HSP60 has previously been shown to be an independent risk factor for congestive heart failure. Recently, increased HSP60 values have been shown to be associated with increased mortality in patients hospitalized with acute heart failure. The purpose of our study was to determine whether HSP 60 is an independent predictor of in-hospital or short-term mortality in patients with acute ST segment elevation myocardial infarction (STEMI) and to assess whether it may be used as an early predictor of in-hospital heart failure or cardiogenic shock development in the same population. Methods A total of 221 patients over 18 years of age presenting within 12 hours after the onset of symptoms with STEMI between 2011 and 2013 were enrolled to our study. Our study was designed as a prospective cohort. Several clinical conditions, such as clinical heart failure, development of cardiogenic shock and death during hospitalization were recorded together with the data pertaining to the length of hospital stay, MI localization, revascularization strategy and risk factors associated with coronary heart disease. Patients were called 1 month after discharge to find out if anyone had died. Results HSP 60 values were significantly higher in patients who died during hospitalization (P=0.004) or within 1 month after discharge (P=0.020). These results were independent from other factors associated with mortality following STEMI. Significant association was found between HSP60 value and in-hospital development of cardiogenic shock (P=0.03) or heart failure (P=0.03). Conclusion HSP60 was found to be independently associated with increased mortality in patients … |
Anahtar Kelimeler |
Makale Türü | Özgün Makale |
Makale Alt Türü | Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale |
Dergi Adı | Journal of Surgery and Medicine |
Dergi ISSN | 2602-2079 |
Dergi Tarandığı Indeksler | Directory of Open Access Journals (DOAJ), JournalTOCs, SciLit, Google Scholar, CrossRef (DOI), Academic Keys, International Society for Research Activity (ISRA), ResearchBib, International Scientific Indexing (ISI), Directory of Research Journals Indexing (DRJI), International Institute of Organized Researches (I2OR), Science Library Index, JournalFactor, scientific World Index (SCIWIN), General Impact Factor, Journal Impact Factor (JIFACTOR), Scientific Indexing Service (SIS), J-Gate, Rootindexing, SHERPA/RoMEO, COSMOS IF, International Committee of Medical Journal Editors (ICMJE), ROAD, CiteFactor, BielefeldAcademic Search Engine (BASE) |
Makale Dili | İngilizce |
Basım Tarihi | 02-2020 |
Cilt No | 4 |
Sayı | 2 |
Sayfalar | 130 / 134 |
Makale Linki | https://dergipark.org.tr/en/doi/10.28982/josam.601334 |