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The value of heat shock protein (HSP) 60 on in-hospital and short-term prognosis in patients with acute ST segment elevation myocardial infarction   
Yazarlar (8)
Recep Karataş
Mustafa Çelik
Kırşehir Ahi Evran Üniversitesi, Türkiye
Ahmet Yılmaz
Fikret Keleş
Nazif Aygül
Selçuk Üniversitesi, Türkiye
Hüsamettin Vatansev
Selçuk Üniversitesi, Türkiye
Doç. Dr. Erdoğan SÖKMEN Doç. Dr. Erdoğan SÖKMEN
Kırşehir Ahi Evran Üniversitesi, Türkiye
Ahmet Erseçgin
Devamını Göster
Özet
Aim HSP60 has previously been shown to be an independent risk factor for congestive heart failure. Recently, increased HSP60 values have been shown to be associated with increased mortality in patients hospitalized with acute heart failure. The purpose of our study was to determine whether HSP 60 is an independent predictor of in-hospital or short-term mortality in patients with acute ST segment elevation myocardial infarction (STEMI) and to assess whether it may be used as an early predictor of in-hospital heart failure or cardiogenic shock development in the same population. Methods A total of 221 patients over 18 years of age presenting within 12 hours after the onset of symptoms with STEMI between 2011 and 2013 were enrolled to our study. Our study was designed as a prospective cohort. Several clinical conditions, such as clinical heart failure, development of cardiogenic shock and death during hospitalization were recorded together with the data pertaining to the length of hospital stay, MI localization, revascularization strategy and risk factors associated with coronary heart disease. Patients were called 1 month after discharge to find out if anyone had died. Results HSP 60 values were significantly higher in patients who died during hospitalization (P=0.004) or within 1 month after discharge (P=0.020). These results were independent from other factors associated with mortality following STEMI. Significant association was found between HSP60 value and in-hospital development of cardiogenic shock (P=0.03) or heart failure (P=0.03). Conclusion HSP60 was found to be independently associated with increased mortality in patients …
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale
Dergi Adı Journal of Surgery and Medicine
Dergi ISSN 2602-2079
Dergi Tarandığı Indeksler Directory of Open Access Journals (DOAJ), JournalTOCs, SciLit, Google Scholar, CrossRef (DOI), Academic Keys, International Society for Research Activity (ISRA), ResearchBib, International Scientific Indexing (ISI), Directory of Research Journals Indexing (DRJI), International Institute of Organized Researches (I2OR), Science Library Index, JournalFactor, scientific World Index (SCIWIN), General Impact Factor, Journal Impact Factor (JIFACTOR), Scientific Indexing Service (SIS), J-Gate, Rootindexing, SHERPA/RoMEO, COSMOS IF, International Committee of Medical Journal Editors (ICMJE), ROAD, CiteFactor, BielefeldAcademic Search Engine (BASE)
Makale Dili İngilizce
Basım Tarihi 02-2020
Cilt No 4
Sayı 2
Sayfalar 130 / 134
Makale Linki https://dergipark.org.tr/en/doi/10.28982/josam.601334
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Google Scholar 3

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