First Report of the Synthesis, Characterization, DFT Calculations of the New Oxoethyl Methacrylate and o-Acetamide and Evaluation of Antimicrobial, Antibiofilm and Antioxidant Effect
Yazarlar (5)
Nevin Çankaya Uşak Üniversitesi, Türkiye
Safiye Elif Korcan Usak University, Ermenistan
Naki Çolak Hitit Üniversitesi, Türkiye
Öğr. Gör. Büşra AYDIN Kırşehir Ahi Evran Üniversitesi, Türkiye
Prof. Dr. Emine TANIŞ Kırşehir Ahi Evran Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Polycyclic Aromatic Compounds (Q2) | ||
| Dergi ISSN | 1040-6638 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 07-2023 |
| Kabul Tarihi | 12-04-2026 | Yayınlanma Tarihi | – |
| Cilt / Sayı / Sayfa | 43 / 6 / 5139–5157 | DOI | 10.1080/10406638.2022.2097271 |
| Makale Linki | http://dx.doi.org/10.1080/10406638.2022.2097271 | ||
| Özet |
| In this study, 2-chloro-N-(2-methoxyphenyl)acetamide (o-acetamide) and 2-(2-methoxyphenylamino)-2-oxoethyl methacrylate (2MPAEMA), which is unreported in the literature were synthesized and characterized. Characterization of the 2MPAEMA and o-acetamide were performed by elemental analyses, FT-IR, 1H and 13C NMR spectroscopic techniques. Global reactivity descriptors such as HOMO-LUMO gaps and chemical hardness, electronegativity, chemical potential, electrophilicity index, as well as NBO, MEB analyzes were performed at the DFT/B3LYP/6-311++G(d,p) level and interpreted in detail. From the theoretical results, in parallel with the experimental results, it was concluded that the o-acetamide compound had greater stability and lower toxicity than the 2MPAEMA compound. In biological studies, in vitro antioxidant activity was explained by DPPH. Agar-well diffusion effect and disk diffusion method … |
| Anahtar Kelimeler |
| 2-(2-methoxyphenylamino)-2-oxoethyl methacrylate | Antibacterial | antibiofilm | antifungal | antioxidant | DFT |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 16 |
| Scopus | 9 |
| Web of Science | 12 |