Oxidative effects of extremely low frequency magnetic field and radio frequency radiation on testes tissues of diabetic and healthy rats
   
Yazarlar (5)
Dr. Öğr. Üyesi Dilek KUZAY AKSOY Kırşehir Ahi Evran Üniversitesi, Türkiye
C. Ozer
Gazi Üniversitesi, Türkiye
B. Sirav
Gazi Üniversitesi, Türkiye
A. G. Canseven
Gazi Üniversitesi, Türkiye
N. Seyhan
Gazi Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Bratislava Medical Journal (Q3)
Dergi ISSN 0006-9248 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2017
Cilt / Sayı / Sayfa 118 / 5 / 278–282 DOI 10.4149/BLL_2017_055
Makale Linki http://www.elis.sk/index.php?page=shop.product_detailsflypage=flypage.tplproduct_id=5219category_id=135option=com_virtuemart
Özet
With the development of technology, people are increasingly under the exposure of electromagnetic fi elds. Individuals with chronic diseases such as diabetes are now long-term exposed to Radio Frequency-RF radiation and extremely low frequency (ELF) magnetic fi elds (MFs). The purpose of this present study is to investigate oxidative effects and antioxidant parameters of ELF MFs and RF radiation on testis tissue in diabetic and healthy rats. Wistar male rats were divided into 10 groups. Intraperitoneal single dose STZ (65 mg/kg) dissolved in citrate buffer (0.1M (pH 4.5)) was injected to diabetes groups. ELF MFs and RF radiation were used as an electromagnetic exposure for 20 min/day, 5 days/week for one month. Testis tissue oxidant malondialdehyde (MDA), and antioxidants glutathione (GSH), and total nitric oxide (NOx) levels were determined. The results of ANOVA and Mann-Whitney tests were compared; p < 0.05 was considered signifi cant. ELF and RF radiation resulted in an increase in testicular tissue MDA and NOX levels (p < 0.05), and caused a decrease in GSH levels (p < 0.05) in both healthy and diabetic rats, yet more distinctively in diabetic rats. The most pronounced effect was recorded in D-RF + ELF group (p < 0.005). Both radiation practices increased the oxidative stress in testis tissue while causing a decrease in antioxidant level which was more distinctive in diabetic rats.
Anahtar Kelimeler
Diabetes mellitus | ELF magnetic field | Oxidative effect | Rat | RF radiation | Testes