Effects of 2600 Mhz Radiofrequency Radiation and Melatonin on Skin and Liver Tissue Hydroxyprolin Levels of Male Rats
Yazarlar (7)
Sinem Oruç
Gazi University, Faculty Of Medicine, Türkiye
Kevser Delen
Gazi University, Faculty Of Medicine, Türkiye
Armagan Yardim
Gazi University, Faculty Of Medicine, Türkiye
Bahriye Sirav Aral
Gazi University, Faculty Of Medicine, Türkiye
Dr. Öğr. Üyesi Dilek KUZAY AKSOY
Kırşehir Ahi Evran Üniversitesi, Türkiye
Cemile Merve Seymen
Gazi University, Faculty Of Medicine, Türkiye
Gülnur Take Kaplanoglu
Gazi University, Faculty Of Medicine, Türkiye
| Makale Türü |
Özgün Makale
(ESCI dergilerinde yayınlanan tam makale)
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| Dergi Adı | Gazi Medical Journal | ||
| Dergi ISSN | 2147-2092 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | E-SCI | ||
| Makale Dili | Türkçe | Basım Tarihi | 04-2023 |
| Cilt / Sayı / Sayfa | 34 / 2 / 141–144 | DOI | 10.12996/gmj.2023.29 |
| Makale Linki | http://dx.doi.org/10.12996/gmj.2023.29 | ||
| Özet |
| Objective: In the present study, the effect of 2600 MHz radiofrequency radiation (RFR) exposure, and melatonin treatment on skin and liver tissue hydroxyproline (Hyp) levels were evaluated. Methods: In the study, 2600 MHz RFR application was performed by Rohde & Schwartz Radiofrequency signal generator via ETS-Lindgren horn antenna. 36 Wistar albino male rats were randomly divided into 6 groups (n = 6); Control, sham, RFR, control + Melatonin, Sham + Melatonin, RFR + Melatonin. RFR was applied to the related groups for 30 days (5 days/week) for 30 minutes a day. Average electric field value is 21.74 V / m. Melatonin groups were subcutaneously injected with melatonin (10 mg/kg) for 30 days. At the end of the experiment, Hyp levels were measured in the skin and liver tissues. Results: Hyp levels in skin tissue decreased significantly in RFR treated groups compared to the control and sham groups (p <0.05). Also, Hyp levels in skin tissue decreased significantly in RFR + melatonin treated group compared to the control, sham and sham+melatonin groups. No changes in Hyp levels in liver tissue were determined. Conclusion: In this study, RFR exposure leads to significant changes in skin Hyp levels but not liver tissue. This effect is thought to be due to the closer the skin tissue to the surface. |
| Anahtar Kelimeler |
| hydroxyproline | liver tissue | melatonin | Radiofrequency radiation | rat | skin tissue |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları |