| Yazarlar |
Sinem Oruç
Fırat Üniversitesi, Türkiye |
|
Kevser Delen
Türkiye |
|
Armağan Yardım
|
|
Bahriye Aral
Gazi Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Dilek KUZAY AKSOY
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Cemile Merve Seymen
Türkiye |
|
Gülnur Take Kaplanoğlu
Türkiye |
| Özet |
| Objective: In the present study, the effect of 2600 MHz radiofrequency radiation (RFR) exposure, and melatonin treatment on skin and liver tissue hydroxyproline (Hyp) levels were evaluated. Methods: In the study, 2600 MHz RFR application was performed by Rohde & Schwartz Radiofrequency signal generator via ETS-Lindgren horn antenna. 36 Wistar albino male rats were randomly divided into 6 groups (n = 6); Control, sham, RFR, control + Melatonin, Sham + Melatonin, RFR + Melatonin. RFR was applied to the related groups for 30 days (5 days/week) for 30 minutes a day. Average electric field value is 21.74 V / m. Melatonin groups were subcutaneously injected with melatonin (10 mg/kg) for 30 days. At the end of the experiment, Hyp levels were measured in the skin and liver tissues. Results: Hyp levels in skin tissue decreased significantly in RFR treated groups compared to the control and sham groups (p <0.05). Also, Hyp levels in skin tissue decreased significantly in RFR + melatonin treated group compared to the control, sham and sham+melatonin groups. No changes in Hyp levels in liver tissue were determined. Conclusion: In this study, RFR exposure leads to significant changes in skin Hyp levels but not liver tissue. This effect is thought to be due to the closer the skin tissue to the surface. |
| Anahtar Kelimeler |
| hydroxyproline | liver tissue | melatonin | Radiofrequency radiation | rat | skin tissue |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | ESCI dergilerinde yayımlanan tam makale |
| Dergi Adı | Gazi Med j |
| Dergi ISSN | 2147-2092 |
| Dergi Tarandığı Indeksler | E-SCI |
| Makale Dili | Türkçe |
| Basım Tarihi | 04-2023 |
| Cilt No | 34 |
| Sayı | 2 |
| Sayfalar | 141 / 144 |
| Doi Numarası | 10.12996/gmj.2023.29 |
| Makale Linki | http://dx.doi.org/10.12996/gmj.2023.29 |
| Atıf Sayıları |
