Causative pathogens and antibiotic resistance in diabetic foot infections: A prospective multi-center study
Yazarlar (1)
Prof. Dr. Mustafa Kasım KARAHOCAGİL Kırşehir Ahi Evran Üniversitesi, Türkiye
| Bildiri Türü | Tebliğ/Bildiri | Bildiri Dili | İngilizce |
| Bildiri Alt Türü | Tam Metin Olarak Yayınlanan Tebliğ (Uluslararası Kongre/Sempozyum) | ||
| Bildiri Niteliği | |||
| DOI Numarası | 10.1016/j.jdiacomp.2016.02.013 | ||
| Kongre Adı | Journal of Diabetes and Its Complications | ||
| Kongre Tarihi | / | ||
| Basıldığı Ülke | Basıldığı Şehir | ||
| UAK Araştırma Alanları |
Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji
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| Özet |
| Aim Clinical practice guidelines for the management of diabetic foot infections developed by the Infectious Diseases Society of America (IDSA) are commonly used worldwide. The issue of whether or not these guidelines need to be adjusted for local circumstances, however, has seldom been assessed in large prospective trials. Methods The Turk-DAY trial was a prospective, multi-center study in which infectious disease specialists from centers across Turkey were invited to participate (NCT02026830). Results A total of 35 centers throughout Turkey enrolled patients in the trial. Overall, investigators collected a total of 522 specimens from infected diabetic foot wounds for culture from 447 individual patients. Among all isolates, 36.4% were gram-positive organisms, with Staphylococcus aureus the most common among these (11.4%). Gram-negative organisms constituted 60.2% of all the isolates, and the most commonly isolated gram-negative was Escherichia coli (15%). The sensitivity rates of the isolated species were remarkably low for several antimicrobials used in the mild infection group. Conclusions Based on our findings, several of the antimicrobials frequently used for empirical treatment, including some also recommended in the IDSA guidelines, would not be optimal for treating diabetic foot infections in Turkey. Although the IDSA guideline recommendations may be helpful to guide empiric antimicrobial therapy of DFIs, they should be adjusted to local conditions. |
| Anahtar Kelimeler |
| Antibiotic therapy | Diabetic foot | Guideline | Infection | Turkey |
Science Direct
Causative pathogens and antibiotic resistance in diabetic foot infections: A prospective multi-center study
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Scopus | 58 |