Chemical Composition, Antioxidant Capacity, Acetyl-and Butyrylcholinesterase Inhibitory Activities of the Essential Oil of Thymus haussknechtii Velen.
Yazarlar (7)
Handan G Sevindik
Temel Özek
K Özden Yerdelen
Prof. Dr. Mehmet Mustafa ÖNAL Türkiye
Hilal Özbek
Zühal Güvenalp
L Ömür Demirezer
Kırşehir Ahi Evran Üniversitesi
Kırşehir Ahi Evran Üniversitesi
| Makale Türü |
Özgün Makale
(Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale)
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| Dergi Adı | Records of Natural Products | ||
| Makale Dili | – | Basım Tarihi | 01-2016 |
| Cilt / Sayı / Sayfa | 10 / 4 / 503–0 | DOI | – |
| Makale Linki | http://www.acgpubs.org/doc/2018080619423860-RNP-EO-1501_006.pdf | ||
| UAK Araştırma Alanları |
Betonarme Yapılar
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| Özet |
| The chemical composition of the essential oil from the aerial parts of Thymus haussknechtii Velen. was analyzed by using gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS). The major component of the essential oil was thymol (52.2%). Total phenolic content of the essential oil was determined as 132.9 µg gallic acid equivalent. The antioxidant capacity was evaluated by DPPH free radical, superoxide anion radical and hydrogen peroxide scavenging activities along with ferrous ion-chelating power test, ABTS radical cation decolorization assay and ferric thiocyanate methods. In addition to antioxidant activity, anticholinesterase activity of the essential oil was also evaluated. It exhibited inhibitory activities on AChE and BuChE which play an important role in Alzheimer’s disease, along with significant antioxidant activity. |
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