Comparison of some biological activities and catechin tannin contents of two Juniperus and Prunus species
Yazarlar (10)
Hafize Yuca
Hakkı Cem Demircan
Bilge Aydın
Prof. Dr. Mehmet Mustafa ÖNAL Türkiye
Enes Tekman
Ayşe Civaş
Mohaddeseh Nobarirezaeyeh
Gamze Göger
Songül Karakaya
Prof. Dr. Zuhal Güvenalp Kırşehir Ahi Evran Üniversitesi
| Makale Türü | Özgün Makale (Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Faculty of Pharmacy of Ankara University | ||
| Makale Dili | – | Basım Tarihi | 05-2023 |
| Cilt / Sayı / Sayfa | 47 / 2 / 650–666 | DOI | – |
| Makale Linki | https://dergipark.org.tr/en/pub/jfpanu/article/1218845 | ||
| UAK Araştırma Alanları |
Betonarme Yapılar
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| Özet |
| Objective Qualitative and quantitative determination of catechin in fruits of J. communis var. saxatilis, J. oxycedrus subsp. oxycedrus, P. spinosa, and P. cerasifera was analyzed by LC-MS/MS using standards. Antidiabetic, antimicrobial, and antioxidant activities of fruit and cone extracts of these plants were evaluated. Qualitative analysis of secondary metabolites was also done. Material and Method Antimicrobial activity was done with MIC. ABTS·+ and DPPH• scavenging activies were used antioxidant activity. α-Amylase and α-glucosidase inhibition assays were done for antidiabetic activity. Result and Discussion JCS (IC50 = 578 ± 20 μg/ml), JOO (IC50 = 3706 ± 52 μg/ml), and PS (IC50 = 313 ± 7 μg/ml) extracts were observed to show a higher activity than acarbose (IC50 = 4061 ± 146 μg/ml). J. communis var. saxatilis fruit extract was observed with MIC values between (312.5 -2500 µg/ml) against all microorganisms. JCS extract has the highest phenolic composition and JOO has the lowest phenolic composition (µg GAE/ mg extract). JCS extract indicated the highest antioxidant activity. It was determined that plant containing the highest catechin (1173.3±5.77 ng/ml) and epigallocatechin (208±7.21 ng/ml) was JCS. In this research, it can be said that JCS with the highest tannin content shows the highest effects. |
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