Phytochemical Traits and Biological Activity of Satureja hortensis and Satureja macrantha as Culinary Spices Using GC–MS/MS and LC–MS/MS Techniques
Yazarlar (9)
Pardis Elmdoustazar
Bilge Aydın
Hafize Yuca
Mehmet Karadayı
Yusuf Gülşahin
Betül Demirci
Songül Karakaya
Prof. Dr. Zühal Güvenalp Kırşehir Ahi Evran Üniversitesi
Makale Türü Özgün Makale (Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale)
Dergi Adı Food Science & Nutrition
Makale Dili Basım Tarihi 01-2025
Cilt / Sayı / Sayfa 13 / 8 / – DOI 10.1002/fsn3.70733
Makale Linki https://onlinelibrary.wiley.com/doi/abs/10.1002/fsn3.70733
UAK Araştırma Alanları
Betonarme Yapılar
Özet
This study evaluates the antidiabetic, anti‐Alzheimer, antimicrobial, and antioxidant activities of water and methanol extracts, as well as essential oils, from Satureja macrantha and Satureja hortensis. Chemical characterization was conducted using LC–MS/MS for phenolic profiles and GC–MS for essential oil composition. Biological activities were assessed via DPPH˙ and ABTS˙+ assays for antioxidant capacity, α‐glucosidase and α‐amylase inhibition for antidiabetic potential, cholinesterase inhibition for anti‐Alzheimer activity, and the microdilution method for antimicrobial effects. Genotoxicity and antigenotoxicity were evaluated using Ames and Allium cepa assays. Rosmarinic acid was most abundant in S. macrantha water extract (50.687.02 ng/mL), while thymol (45.1%) and p‐cymene (45.8%) were identified as major oil components. S. hortensis essential oil showed the strongest α‐glucosidase (41.33 …
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