Association Between Pan-Immune-Inflammation Value and Dipper/Non-Dipper Status in Newly Diagnosed Hypertensive Patients
  
Yazarlar (3)
Dr. Öğr. Üyesi Muhammet Salih ATEŞ Kırşehir Ahi Evran Üniversitesi, Türkiye
Dr. Öğr. Üyesi Alp YILDIRIM Kırşehir Ahi Evran Üniversitesi, Türkiye
Prof. Dr. Erdoğan SÖKMEN Kırşehir Ahi Evran Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of Inflammation Research (Q2)
Dergi ISSN 1178-7031 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili Türkçe Basım Tarihi 05-2025
Cilt / Sayı / Sayfa – / 0 / – DOI 10.2147/JIR.S522032
Makale Linki https://doi.org/10.2147/jir.s522032
Özet
PurposeThis study aimed to investigate the association between the pan-immune-inflammation value (PIV) and dipper/non-dipper status in newly diagnosed hypertensive (HT) patients. Given the role of systemic inflammation in circadian blood pressure (BP) pattern, we hypothesized that elevated PIV levels would be linked to an impaired nocturnal BP decline.Patients and MethodsA total of 725 newly diagnosed hypertensive patients and 343 normotensive controls were prospectively included in the study. The HT patients were further classified as dipper (n=339) or non-dipper (n=386) based on 24-hour ambulatory BP monitoring (ABPM). PIV was calculated as (neutrophil count × platelet count × monocyte count) / lymphocyte count. Multivariate logistic regression analysis was performed to assess the independent association between PIV quartiles and non-dipper status. Receiver operating characteristic (ROC …
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