Effects of hirudotherapy on liver functions, lipid profile, and insulin sensitivity in rats with metabolic syndrome
Yazarlar (6)
Dr. Öğr. Üyesi Alican BİLDEN Kırşehir Ahi Evran Üniversitesi, Türkiye
Dr. Öğr. Üyesi Seda KOÇAK Kırşehir Ahi Evran Üniversitesi, Türkiye
Doç. Dr. Halime TOZAK YILDIZ Kırşehir Ahi Evran Üniversitesi, Türkiye
Fatih Çakır Batman University, Türkiye
Arş. Gör. Merve KAHRAMAN HÜSEYİN Kırşehir Ahi Evran Üniversitesi, Türkiye
Prof. Dr. Muttalip ÇİÇEK Kırşehir Ahi Evran Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | BMC Complementary Medicine and Therapies (Q1) | ||
| Dergi ISSN | 2662-7671 Dergi Bilgileri (2026) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2026 |
| Cilt / Sayı / Sayfa | 26 / 1 / 34–13 | DOI | 10.1186/s12906-025-05241-x |
| Makale Linki | https://link.springer.com/article/10.1186/s12906-025-05241-x | ||
| UAK Araştırma Alanları |
Tıbbi Parazitoloji (Tıbbi Mikrobiyoloji)
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| Özet |
| BackgroundMetabolic syndrome (METS) is a multifactorial cardiometabolic disorder characterized by abdominal obesity, insulin resistance, hypertension, dyslipidemia, and hyperglycemia, substantially increasing the risk of type 2 diabetes and cardiovascular diseases. The variable effectiveness of lifestyle and pharmacological interventions has heightened interest in complementary approaches. Hirudotherapy, containing a wide range of bioactive compounds, may offer therapeutic benefits. This study aimed to evaluate the effects of hirudotherapy on metabolic parameters in a rat model of METS.MethodsTwenty-four male Wistar rats were divided into four groups: Control (n = 6), METS (n = 6), METS + 4-week hirudotherapy (n = 6), and METS + 8-week hirudotherapy (n = 6). METS was induced through a modified high-fat and fructose-enriched diet. The effects of hirudotherapy on liver enzymes (AST … |
| Anahtar Kelimeler |
| Alternative treatment | Hirudotherapy | Metabolic syndrome | Therapeutic effect |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Scopus | 1 |