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Akademisyenler > Ebru ÇÖTELİ > Yayın Detayı

Crystal structure, spectroscopic characterization, DFT calculations, and antidiabetic activity of silver (I) perchlorate complex with methyl 6-quinolyl ether  
Yazarlar (5)
Merve Nurhan Guney
Gazi Üniversitesi, Türkiye
Ceyhun Kucuk
Zonguldak Bulent Ecevit University, Türkiye
Senay Yurdakul
Gazi Üniversitesi, Türkiye
Namık Özdemir
Ondokuz Mayis Üniversitesi, Türkiye
Doç. Dr. Ebru ÇÖTELİ Doç. Dr. Ebru ÇÖTELİ
Kırşehir Ahi Evran Üniversitesi, Türkiye
Devamını Göster
Özet
The [Ag(C10H9NO)2]ClO4 complex was synthesized from the methyl 6-quinolyl ether (6-MQ) (C10H9NO) molecule, and this new structure was characterized by spectroscopic methods such as single-crystal X-ray diffraction, FT-IR, FT-Ra, ¹H, and ¹³C NMR. In addition, these spectroscopic data were combined with DFT calculations. The X-ray diffraction analysis revealed that the Ag(I) complex crystallized in the monoclinic system with the P21/n. The asymmetric unit of the compound comprises one Ag(I) cation, two methoxyquinoline ligands with the same distance [2.134 Å], and one ClO₄⁻ anion. Computational studies were performed by using the DFT approach on the present complex to get insight into the structural parameters, spectral characteristics, and electronic properties. The characterization results were found to be consistent with the proposed structure of the complex, and the DFT approach supported the experimental results. Also, the antidiabetic activity of the methyl 6-quinolyl ether silver perchlorate complex was investigated. It was determined that the complex had both α-amylase and α-glucosidase enzyme inhibition. Both enzyme inhibitory concentrations (IC50) of the complex with the standard drug acarbose were calculated. As a result, it was determined that this synthesized complex had antidiabetic properties.
Anahtar Kelimeler
Antidiabetic activity | Crystal structure | Methyl 6-quinolyl ether | Silver perchlorate complex | Vibrational spectra
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Journal of Molecular Structure
Dergi ISSN 0022-2860 Wos Dergi Scopus Dergi
Dergi Grubu Q2
Makale Dili İngilizce
Basım Tarihi 02-2026
Cilt No 1352
Sayı 1
DOI Numarası 10.1016/j.molstruc.2025.144550
Science Direct
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Crystal structure, spectroscopic characterization, DFT calculations, and antidiabetic activity of silver (I) perchlorate complex with methyl 6-quinolyl ether

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