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Relationship of the atherogenic index of plasma and cha₂ds₂-vasc scores patients with acute st-segment elevation myocardial infarction and non-st- segment myocardial infarction   
Yazarlar (5)
Samet Altunbas
Mamak State Hosp, Türkiye
Doç. Dr. Hacı Mehmet ÇALIŞKAN Doç. Dr. Hacı Mehmet ÇALIŞKAN
Kırşehir Ahi Evran Üniversitesi, Türkiye
Doç. Dr. Erdoğan SÖKMEN Doç. Dr. Erdoğan SÖKMEN
Kırşehir Ahi Evran Üniversitesi, Türkiye
Burak Sahin
Kirsehir Training & Res Hosp, Türkiye
Omer Jaradat
Kirsehir Training & Res Hosp, Türkiye
Devamını Göster
Özet
Aim: This study assessed the relationship between the CHA(2)DS(2)-VASc score, the atherogenic index of plasma (AIP), monocyte-HDL ratio (MHR), platelet-lymphocyte ratio (PLR), neutrophil-lymphocyte ratio (NLR), and myocardial infarction (MI) types (STEMI/NSTEMI) in emergency department patients, aiming to identify correlations between these parameters.Materials and Methods: Conducted as a retrospective study at K & imath;r & scedil;ehir Training Education and Research Hospital (2020-2023), this research included 200 STEMI patients, 200 NSTEMI patients, and 200 healthy controls.Results: The mean age of participants was 60.70 +/- 12.33. Significant differences emerged across groups in CHA(2)DS(2)-VASc, AIP, PLR, NLR, and MHR. The CHA(2)DS(2)-VASc score was higher in NSTEMI versus STEMI and controls. AIP was elevated in both MI groups versus controls. MHR was higher in STEMI than in controls, while NLR was elevated in both MI groups. A weak positive correlation existed between CHA(2)DS(2)-VASc and NLR/PLR and AIP and MHR. Each 1-unit increase in CHA(2)DS(2)-VASc, AIP, and NLR raised MI risk by 1.60, 3.24, and 2.59 times, respectively, whereas PLR reduced risk by 1.013 times per unit.Discussion: All atherosclerosis-related inflammatory markers were elevated in MI patients. CHA(2)DS(2)-VASc showed no significant correlation with AIP but was notably higher in NSTEMI, while AIP was elevated in both MI groups. CHA(2)DS(2)-VASc demonstrates strong predictive value for NSTEMI in clinical/emergency settings, whereas AIP lacks significance for specific MI subgroups. Broader multicenter studies are required to clarify their utility in MI risk stratification.
Anahtar Kelimeler
atherogenic index of plasma | St-segment elevation myocardial infarction | non-St-segment elevation myocardial infarction | Cha(2)Ds(2)-VASc score | neutrophil-lymphocyte ratio
Makale Türü Özgün Makale
Makale Alt Türü ESCI dergilerinde yayınlanan tam makale
Dergi Adı Annals of Clinical and Analytical Medicine
Dergi ISSN 2667-663X Wos Dergi
Dergi Tarandığı Indeksler eSCI
Makale Dili Türkçe
Basım Tarihi 01-2025
Cilt No 16
Sayı 11
Sayfalar 833 / 838
DOI Numarası 10.4328/ACAM.22652
Makale Linki https://doi.org/10.4328/acam.22652