| Yazarlar (5) |
Dr. Öğr. Üyesi Gamze TURNA SALTOĞLU
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Erkan DULKADİROĞLU
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Duygu Tozcu Yılmaz
Türkiye |
Doç. Dr. Bilal İLANBEY
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Prof. Dr. Ülken Tunga BABAOĞLU
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| Results:Serum preptin levels were significantly higher in MetS patients compared to the control group (53.77 pg/mL vs. 40.77 pg/mL, p< 0.001). MetS patients also had higher triglyceride, cholesterol, low-density lipoprotein cholesterol (LDL-C), fasting glucose, Hemoglobin A1c (HbA1c), insulin, and Homeostatic model assessment of insulin resistance (HOMA-IR) values compared to controls (all p< 0.001). A positive correlation was found between serum preptin, insulin (r= 0.432,% 95 CI: 0.07-0.57, p= 0.0050), and HOMA-IR (r= 0.426,% 95 CI: 0.08-0.56, p= 0.0060) in the MetS group.Conclusions:The results indicate that serum preptin levels are significantly elevated in MetS patients. Furthermore, high serum preptin levels were positively correlated with insulin and insulin resistance. These results suggest that preptin may be involved in the insulin resistance pathway via insulin-like growth factor II (IGF-II) modulation. Therefore, further extensive studies are required to fully understand the precise role in MetS and underlying mechanisms of preptin. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | Archives of Medical Science |
| Dergi ISSN | 1734-1922 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q1 |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2025 |
| Doi Numarası | 10.5114/aoms/209463 |
| Makale Linki | https://doi.org/10.5114/aoms/209463 |
| Atıf Sayıları |
