| Yazarlar (4) |
|
Ahi Evran Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Cihat ÖZTÜRK
Ahi Evran Üniversitesi, Türkiye |
Prof. Dr. Elif SEVİM
Ahi Evran Üniversitesi, Türkiye |
|
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| Objectives To specifically assess the prevalence and transferability of PMQR genes in quinolone-resistant A. baumannii clinical isolates collected between September 2021 and December 2022 in Kırşehir, Turkey, using molecular techniques and conjugation assays. Methods Twenty-nine non-duplicate quinolone-resistant A. baumannii isolates were analyzed. Identification and susceptibility were determined via VITEK® 2. PMQR genes (qnrA, qnrB, qnrC, qnrD, qnrS, qepA, oqxA, oqxB) and aac(6')-Ib-cr were detected by PCR. Conjugation experiments were performed using brothmating method to the transferability of PMQR genes. Results In 29 A. baumannii isolates, qnrB, oqxA, aac(6')-Ib-cr, qnrS and oqxB genes were detected as 82.8%, 55.2%, 51.7%, 10.3% and 10.3%, respectively. No amplification was observed for qnrA, qnrC, qnrD, or qepA. Conjugation assay confirmed the horizontal transfer of the qnrB ... |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SCOPUS dergilerinde yayınlanan tam makale |
| Dergi Adı | Microbes and Infectious Diseases |
| Dergi ISSN | 2682-4132 Scopus Dergi |
| Dergi Tarandığı Indeksler | Scopus |
| Makale Dili | İngilizce |
| Basım Tarihi | 02-2026 |