Investigation of plasmid mediated quinolone resistance genes in quinolone-resistant Acinetobacter baumannii isolates
Yazarlar (4)
Duha Nagim Abdalh
Dr. Öğr. Üyesi Cihat ÖZTÜRK
Kırşehir Ahi Evran Üniversitesi, Türkiye
Prof. Dr. Elif SEVİM
Kırşehir Ahi Evran Üniversitesi, Türkiye
Rukiye Akyol
Türkiye
| Makale Türü |
Özgün Makale
(SCOPUS dergilerinde yayınlanan tam makale)
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| Dergi Adı | Microbes and Infectious Diseases | ||
| Dergi ISSN | 2682-4132 Scopus Dergi | ||
| Dergi Tarandığı Indeksler | Scopus | ||
| Makale Dili | İngilizce | Basım Tarihi | 02-2026 |
| Cilt / Sayı / Sayfa | 0 / 0 / – | DOI | 10.21608/mid.2025.415693.3131 |
| Makale Linki | https://doi.org/10.21608/mid.2025.415693.3131 | ||
| Özet |
| Objectives To specifically assess the prevalence and transferability of PMQR genes in quinolone-resistant A. baumannii clinical isolates collected between September 2021 and December 2022 in Kırşehir, Turkey, using molecular techniques and conjugation assays. Methods Twenty-nine non-duplicate quinolone-resistant A. baumannii isolates were analyzed. Identification and susceptibility were determined via VITEK® 2. PMQR genes (qnrA, qnrB, qnrC, qnrD, qnrS, qepA, oqxA, oqxB) and aac(6')-Ib-cr were detected by PCR. Conjugation experiments were performed using brothmating method to the transferability of PMQR genes. Results In 29 A. baumannii isolates, qnrB, oqxA, aac(6')-Ib-cr, qnrS and oqxB genes were detected as 82.8%, 55.2%, 51.7%, 10.3% and 10.3%, respectively. No amplification was observed for qnrA, qnrC, qnrD, or qepA. Conjugation assay confirmed the horizontal transfer of the qnrB ... |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
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