| Yazarlar (1) |
Doç. Dr. Erdoğan SÖKMEN
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| Aim: This study assessed the relationship between the CHA₂DS₂-VASc score, the atherogenic index of plasma (AIP), monocyte-HDL ratio (MHR), plateletlymphocyte ratio (PLR), neutrophil-lymphocyte ratio (NLR), and myocardial infarction (MI) types (STEMI/NSTEMI) in emergency department patients, aiming to identify correlations between these parameters.Materials and Methods: Conducted as a retrospective study at Kırşehir Training Education and Research Hospital (2020–2023), this research included 200 STEMI patients, 200 NSTEMI patients, and 200 healthy controls.Results: The mean age of participants was 60.70±12.33. Significant differences emerged across groups in CHA₂DS₂-VASc, AIP, PLR, NLR, and MHR. The CHA₂DS₂-VASc score was higher in NSTEMI versus STEMI and controls. AIP was elevated in both MI groups versus controls. MHR was higher in STEMI than in controls, while NLR was elevated in both MI groups. A weak positive correlation existed between CHA₂DS₂-VASc and NLR/PLR and AIP and MHR. Each 1-unit increase in CHA₂DS₂-VASc, AIP, and NLR raised MI risk by 1.60, 3.24, and 2.59 times, respectively, whereas PLR reduced risk by 1.013 times per unit. Discussion: All atherosclerosis-related inflammatory markers were elevated in MI patients. CHA₂DS₂-VASc showed no significant correlation with AIP but was notably higher in NSTEMI, while AIP was elevated in both MI groups. CHA₂DS₂-VASc demonstrates strong predictive value for NSTEMI in clinical/emergency settings, whereas AIP lacks significance for specific MI subgroups. Broader multicenter studies are required to clarify their … |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | ESCI dergilerinde yayınlanan tam makale |
| Dergi Adı | Annals of Clinical and Analytical Medicine |
| Dergi Tarandığı Indeksler | |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2025 |
| Doi Numarası | 10.4328/ACAM.22652 |
| Makale Linki | https://doi.org/10.4328/ACAM.22652 |