Production and characterization of bactericidal wound dressing material based on gelatin nanofiber
 
Yazarlar (2)
M. İnal
Kirikkale Üniversitesi, Türkiye
Arş. Gör. Gökçe MÜLAZIMOĞLU Kırşehir Ahi Evran Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı International Journal of Biological Macromolecules (Q1)
Dergi ISSN 0141-8130 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce Basım Tarihi 09-2019
Cilt / Sayı / Sayfa 137 / 1 / 392–404 DOI 10.1016/j.ijbiomac.2019.06.119
Makale Linki https://linkinghub.elsevier.com/retrieve/pii/S0141813019322202
Özet
Gelatin is a biocompatible and biodegradable natural polymer obtained by collagen. Gelatin nanofibers meet all the necessary requirements when used as wound dressing material. However, their lack of antimicrobial properties limits their use. The purpose of this study is to expand the field of use of gelatin by providing it with antimicrobial properties. For this purpose, poly([2-(methacryloyloxy)ethyl] trimethylammonium chloride) (PMETAC), was used. In this study, the polymers were dissolved in formic acid-acetic acid and nanofibers were synthesized by electrospinning. The obtained nanofibers were characterized with SEM, FTIR, and TGA. The antibacterial effect, degradation tests, and cell viability, adhesion and proliferation were investigated. The SEM studies show that the nanofibers are homogeneous and smooth. At the end of 14 days, all nanofibers lost >90% of their mass. The nanofibers containing …
Anahtar Kelimeler
Electrospinning | Gelatin | Nanofiber | Wound dressing | [2-(Methacryloyloxy)ethyl] trimethylammonium chloride)
Science Direct
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Google Scholar 98
Scopus 75
Production and characterization of bactericidal wound dressing material based on gelatin nanofiber

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