| Yazarlar (6) |
Mahmut Sami Metin
|
|
Tugba Tehci
|
|
Ilkay Kolukirik
|
|
Serkan Akogul
|
|
Umran Oner
|
Doç. Dr. Zuhal METİN
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| Symptomatic dermographism (SD) is the most common chronic inducible urticaria (CIndU) type. Thiol/disulfide homeostasis (TDH) and ischemia-modified albumin (IMA) levels are indicators of oxidative stress. Our study aims to investigate the role of thiol/disulfide balance and IMA levels in the pathogenesis of SD. This focus guides our research and helps us to better understand the disease. This cross-sectional study, conducted with utmost care and precision, included 50 SD patients and 50 healthy volunteers. The patients and controls were meticulously evaluated regarding IMA, native thiol, total thiol, and disulfide levels and disulfide/native thiol, disulfide/total thiol, and native thiol/total thiol ratios, ensuring a thorough and reliable understanding of the data. In our study, the patient group demonstrated significantly higher levels of native thiol, total thiol, disulfide, and IMA values than the control group ( < 0.05). In patients with SD, impaired TDH and increased IMA suggest that oxidative stress may play a significant role in the disease pathogenesis, underscoring the importance of our findings. |
| Anahtar Kelimeler |
| Artificial urticaria | ischemia-modified albumin | oxidative stress | symptomatic dermographism | thiol-disulfide homeostasis |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | INDIAN JOURNAL OF DERMATOLOGY |
| Dergi ISSN | 0019-5154 Wos Dergi Scopus Dergi |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 09-2025 |
| Cilt No | 70 |
| Sayı | 5 |
| Sayfalar | 246 / 251 |
| Doi Numarası | 10.4103/ijd.ijd_770_24 |
| Atıf Sayıları |
