| Yazarlar (2) |
Erdoğan Sökmen
|
|
Mustafa Çelik
|
| Özet |
| Aim Although 30-day mortality rates were improved in thesetting of acute ST-elevation myocardial infarction (STMI), the same does nothold true for longer-term mortality rates. The ratios of monocyte tohigh-density lipoprotein cholesterol (MHR) and neutrophil to lymphocyte (NLR)are novel markers with diagnostic and prognostic significance in variousdisease conditions. Our aim was to evaluate the predictive role of MHR and NLRin in-hospital and 3-month overall death in STMI patients treated with percutaneouscoronary intervention (PCI). Material and Methods A total of 184 consecutive STMI patients undergoingPCI were included. NLR, MHR, clinical and demographic characteristics, andsyntax scores were recorded. The patients were divided into two groupsaccording to the median MHR (group 1, n=92; group 2, n=92). In-hospital and3-month overall death were noted as the primary outcome.Results Median MHR was 19.31. In-hospital mortality and 3-month mortality occurred in 14 (15.2%)and 21 (22.8%) patients, respectively. NLR and number of the patients withcardiogenic shock on admission were greater in group 2. No mortality occurredin group 1. In multivariate logistic regression analysis, higher low-densitylipoprotein cholesterol level, higher syntax score and MHR, but not NLR, wereindependently associated both with in-hospital and 3-month overall death. InROC analysis, MHR >36.6 and MHR >46.81 emerged as cut-off values forin-hospital and 3-month mortality, respectively.Conclusion MHR but not NLR may be utilized in the prediction ofin-hospital and 3-month overall death in acute STMI patients treated withprimary PCI. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale |
| Dergi Adı | Turkish Journal of Clinics and Laboratory |
| Dergi Tarandığı Indeksler | |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2019 |
| Cilt No | 10 |
| Sayı | 4 |
| Sayfalar | 459 / 466 |
