| Yazarlar (5) |
Hülya Elmalı Gülbaş
Usak University, Türkiye |
|
Nevin Çankaya
Usak University, Türkiye |
Doç. Dr. Tuncay KARAKURT
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Doç. Dr. Murat MISIR
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Prof. Dr. Serap YALÇIN AZARKAN
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| In this study, a novel copolymer of limonene and N‐cyclohexylacrylamide (LIM‐co‐NCA) was synthesized and extensively characterized for both its physicochemical and biological properties. The chemical structure of the copolymer was confirmed through Fourier transform infrared and proton nuclear magnetic resonance spectroscopic techniques. Gel Permeation Chromatography (GPC) analysis revealed that LIM‐co‐NCA possesses low molecular weight and oligomeric characteristics. Thermal stability was evaluated using thermogravimetric analysis, while its antiproliferative potential was assessed against the HeLa cervical cancer cell line, demonstrating inhibitory effects. This study investigates the stability and binding affinities of Comp1, Comp2, and Comp3 ligands with 3FAA and 6GUB receptors using computational chemistry methods. Ligand geometries were optimized by density functional theory, and … |
| Anahtar Kelimeler |
| antiproliferative effect | density functional theory (DFT) | he-La cell | LIM-co-NCA | MMPBSA | molecular dynamics (MD) |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | Polymers for Advanced Technologies |
| Dergi ISSN | 1042-7147 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q2 |
| Makale Dili | Türkçe |
| Basım Tarihi | 10-2025 |
| Cilt No | 36 |
| Sayı | 10 |
| Doi Numarası | 10.1002/pat.70376 |
| Makale Linki | https://doi.org/10.1002/pat.70376 |
