Effects of liraglutide on the testis of rats with experimental diabetes and ischemia-reperfusion injury
Yazarlar (8)
Sinem Hazir
Gulfidan Coskun
Cukurova University, Türkiye
Cukurova University, Türkiye
Doç. Dr. Leman Sencar Cukurova University, Türkiye
Abdullah Tuli Cukurova University, Türkiye
Öğr. Gör. Ebru Dundar Yenilmez Cukurova University, Türkiye
Prof. Dr. Yusuf Kenan DAĞLIOĞLU Kırşehir Ahi Evran Üniversitesi, Türkiye
Öğr. Gör. Hulya Ozgur Cukurova University, Türkiye
Sait Polat Cukurova University, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | BIOTECHNIC & HISTOCHEMISTRY (Q4) | ||
| Dergi ISSN | 1052-0295 Dergi Bilgileri (2025) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 08-2025 |
| Cilt / Sayı / Sayfa | 100 / 6 / 371–380 | DOI | 10.1080/10520295.2025.2537045 |
| Makale Linki | https://doi.org/10.1080/10520295.2025.2537045 | ||
| UAK Araştırma Alanları |
Sağlık Bilimleri
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| Özet |
| Our study aimed to investigate the antidiabetic, antioxidative, and antiapoptotic effects of liraglutide on the testes of rats with diabetes and ischemia/reperfusion injury. Subjects were divided into three groups: control, diabetes, and torsion groups. Rats with diabetes were further divided into two subgroups such as diabetes and diabetes+Liraglutide groups. The torsion group was divided into three subgroups such as torsion, torsion/detorsion, and torsion/detorsion+Liraglutide groups. Malondialdehyde (MDA), superoxide dismutase (SOD), and testosterone levels were measured from blood samples. Also, testicular tissue samples were examined by light and electron microscopy. Apoptosis was assessed using immunohistochemistry for caspase-3. Degeneration of seminiferous tubules and interstitium was observed in the diabetes, torsion, and torsion/detorsion groups, while Liraglutide treated groups showed normal … |
| Anahtar Kelimeler |
| Diabetes | GLP-1 analog | liraglutide | testis | torsion |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 1 |