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Evaluation of surgical antimicrobial prophylaxis compliance: A multicenter point prevalence study    
Yazarlar (14)
Yasemin Cakir Kiymaz
Cumhuriyet Üniversitesi Tip Fakültesi, Türkiye
Taliha Karakok
Fatsa State Hospital, Türkiye
Baris Manavli
Afyonkarahisar Health Sciences University, Türkiye
Merve Buyukkoruk
Gazi University, Faculty Of Medicine, Türkiye
Cihad Baysal
Cumhuriyet Üniversitesi Tip Fakültesi, Türkiye
Muhammed Fatih Karasin
Kocaeli Üniversitesi, Türkiye
Merve Turker Isik
Unye State Hospital, Türkiye
Dr. Öğr. Üyesi Kübra ERBAY Dr. Öğr. Üyesi Kübra ERBAY
Kırşehir Ahi Evran Üniversitesi, Türkiye
Levent Sensoy
Fatsa State Hospital, Türkiye
Eren Ozturk
Ankara Üniversitesi, Türkiye
Hasan Selcuk Ozger
Gazi University, Faculty Of Medicine, Türkiye
Derya Korkmaz
Afyonkarahisar Health Sciences University, Türkiye
Sila Akhan
Kocaeli Üniversitesi, Türkiye
Alpay Azap
Ankara Üniversitesi, Türkiye
Devamını Göster
Özet
This study aimed to determine the frequency of compliance with surgical antimicrobial prophylaxis (SAP) in Turkey and to identify the causes for noncompliance. This multicenter, prospective, point prevalence study was conducted in 8 hospitals from different regions of Turkey. Patients over 18years who underwent SAP in all hospital surgical units were included. The SAP compliance assessment was carried out under 5 headings: unnecessary prophylaxis, inappropriate drug choice, prolonged prophylaxis, inappropriate dose interval, and inappropriate dosage. The study included 541 patients from 8 centers. About 52.7% (n=285) were female and the median age was 54years (min-max: 18-94). Orthopedics (23.7%) and general surgery (22.2%) were the most common specialties. SAP compliance was 14%. The specialty with the highest rate of inappropriate SAP was orthopedics (97%) and the lowest rate was in ophthalmology (25%). The most common causes of inappropriate SAP were prolonged prophylaxis (92.0%) and inappropriate dose interval (84.6%). Multivariate logistic regression analysis revealed that prolonged surgical time, American Society of Anaesthesiologists (ASA) score 3, and some specialties increased the risk of noncompliance with surgical prophylaxis. This study showed that SAP compliance is low in Turkey and that inappropriateness is caused mostly by prolonged and inappropriate antimicrobial use.
Anahtar Kelimeler
Antibiotic resistance | Antimicrobial stewardship | Surgical prophylaxis
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı AMERICAN JOURNAL OF INFECTION CONTROL
Dergi ISSN 0196-6553 Wos Dergi Scopus Dergi
Dergi Grubu Q2
Makale Dili İngilizce
Basım Tarihi 05-2025
Cilt No 53
Sayı 5
Sayfalar 552 / 558
Doi Numarası 10.1016/j.ajic.2025.01.014