Synthesis of chiral diaza 18-crown-6 ethers from chiral amines and molecular recognition of potassium and sodium salts of amino acids
   
Yazarlar (2)
Prof. Dr. Nadir DEMİREL Dicle Üniversitesi, Türkiye
Y. Bulut
Dicle Üniversitesi, Türkiye
Makale Türü Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale)
Dergi Adı Tetrahedron Asymmetry
Dergi ISSN 0957-4166 Wos Dergi Scopus Dergi
Makale Dili İngilizce Basım Tarihi 09-2003
Cilt / Sayı / Sayfa 14 / 17 / 2633–2637 DOI 10.1016/S0957-4166(03)00594-9
Özet
A practical synthesis of chiral amine precursors 3 and 4 and chiral diaza 18-crown-6 ethers 5, 6 and 7 starting from chiral amines are reported. The molecular recognition of these chiral crown ethers for amino acids potassium and sodium salts has been characterized by UV-vis. The selectivity order is Phe>Thr>Ala. In the case of 6 the cavity of the macrocycle plays an important role in recognition. © 2003 Elsevier Ltd. All rights reserved.
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