Solvent-free synthesis of chiral Schiff-base ligands based on ferrocene under microwave irradiation and application to enantioselective nitroaldol (Henry) reaction
Yazarlar (3)
Gülşen Öztürk Dicle Üniversitesi, Türkiye
Mehmet Çolak Dicle Üniversitesi, Türkiye
Prof. Dr. Nadir DEMİREL Kırşehir Ahi Evran Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Chirality | ||
| Dergi ISSN | 0899-0042 Wos Dergi Scopus Dergi | ||
| Makale Dili | İngilizce | Basım Tarihi | 05-2011 |
| Kabul Tarihi | 12-04-2026 | Yayınlanma Tarihi | – |
| Cilt / Sayı / Sayfa | 23 / 5 / 374–378 | DOI | 10.1002/chir.20934 |
| Makale Linki | https://onlinelibrary.wiley.com/doi/abs/10.1002/chir.20934 | ||
| Özet |
| Chiral Schiff‐bases 3a, 3b, 3c, 3d, 3e, 3f based on ferrocene were designed and synthesized using solvent‐free methods by mixing ferrocene carbaldehyde 1 with amino alcohols and amines 2a, 2b, 2c, 2d, 2e, 2f under microwave irradiation and classical method for the enantioselective nitroaldol (Henry) reaction. The Schiff‐bases were obtained in shorter reaction times and improved yield under microwave irradiation method over classical method. The highest enantioselectivity was observed in ligand 3e (95% ee) when CH2Cl2 was used as solvent. Chirality, 2011. © 2011 Wiley‐Liss, Inc. |
| Anahtar Kelimeler |
| chiral Schiff-bases | ferrocene | Henry reaction | microwave irradiation | nitro aldol reaction |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 8 |
| Web of Science | 7 |