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PROGNOSTIC VALUE OF DYNAMIC THIOL-DISULFIDE HOMEOSTASIS IN PREDICTING HOSPITAL MORTALITY IN HYPOXEMIC RESPIRATORY FAILURE    
Yazarlar (7)
Doç. Dr. Bilal İLANBEY Doç. Dr. Bilal İLANBEY
Kırşehir Ahi Evran Üniversitesi, Türkiye
Duygu Zorlu Karayiğit
Türkiye
Doç. Dr. Hacı Mehmet ÇALIŞKAN Doç. Dr. Hacı Mehmet ÇALIŞKAN
Kırşehir Ahi Evran Üniversitesi, Türkiye
Zamir Kemal Ertürk
Türkiye
Burak Çelik
Doç. Dr. Süleyman ERSOY Doç. Dr. Süleyman ERSOY
Kırşehir Ahi Evran Üniversitesi, Türkiye
Kenan Güçlü
Türkiye
Devamını Göster
Özet
Hypoxemic respiratory failure (HRF) has a PaO2 < 60 mmHg with normal or subnormal PaCO2. The gas exchange is impaired at the level of the alveolo-capillary membrane. HRF is associated with high mortality in hospital, and there is no diagnostic laboratory test to predict this mortality. This study evaluates the possibility of predicting mortality in HRF patients with dynamic thiol-disulfide homeostasis parameters, which are indicators of oxidation state. Sixty-two patients with HRF and 40 healthy controls were included in the study. Dynamic thiol-disulfide parameters were studied from the serum of all participants. Total and native thiol levels were significantly lower in the patients than in the controls (p < 0.05). Disulfide levels were higher in patients who died than survivors (p
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale
Dergi Adı International Journal of Health Services Research and Policy
Dergi ISSN 2602-3482
Dergi Tarandığı Indeksler DOAJ
Makale Dili Türkçe
Basım Tarihi 08-2022
Cilt No 7
Sayı 2
Sayfalar 138 / 145
Doi Numarası 10.33457/ijhsrp.950523
Makale Linki http://dx.doi.org/10.33457/ijhsrp.950523