The relationship of Growth differentiation factor-15 with renal damage and dyslipidemia in non-albuminuric and albuminuric Type-2 Diabetes Mellitus
Yazarlar (2)
Doç. Dr. Hasan Esat YÜCEL Kırşehir Ahi Evran Üniversitesi, Türkiye
Doç. Dr. Bilal İLANBEY Kırşehir Ahi Evran Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(Diğer hakemli uluslarası dergilerde yayınlanan tam makale)
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| Dergi Adı | Medical Science and Discovery | ||
| Dergi ISSN | 2148-6832 | ||
| Dergi Tarandığı Indeksler | Index Copernicus | ||
| Makale Dili | İngilizce | Basım Tarihi | 06-2022 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 10-06-2022 |
| Cilt / Sayı / Sayfa | 9 / 6 / 334–339 | DOI | 10.36472/msd.v9i6.746 |
| Makale Linki | http://dx.doi.org/10.36472/msd.v9i6.746 | ||
| UAK Araştırma Alanları |
İç Hastalıkları
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| Özet |
| Objective: Aim of this study is to investigate the correlation of Growth differentiation factor-15 with renal damage and dyslipidemia in Type-2 Diabetes Mellitus.Material and Method: The study was conducted prospectively with patients diagnosed with Type-2 Diabetes Mellitus. Two groups were formed as non-albuminuric (n: 47) and albuminuric (n: 24). Age, gender, Growth differentiation factor-15, glycemic index, lipid panel, glomerular filtration rate, complete blood count, urine albumin/creatin and urine protein/creatin of the groups were compared, and their correlations were examined.Results: Growth differentiation factor-15, age, and hemoglobin A1c were found to be higher in the albuminuric group, and hemoglobin and hematocrit levels were found to be lower. A positive correlation of Growth differentiation factor-15 with spot urine albumin/creatin and protein/creatin was observed in the albuminuric group. In the non-albuminuric group, positive correlation was observed with Triglyceride and a negative correlation with high-density lipoprotein cholesterol. Negative correlation of Growth differentiation factor-15 glomerular filtration rate was detected in all participants.Conclusions: Growth differentiation factor-15 has been found positively associated with albuminuria and high triglyceride levels in Type-2 Diabetes Mellitus. It is negatively correlated with glomerular filtration rate and high-density lipoprotein cholesterol. It is strongly associated with renal damage and dyslipidemia. |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
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| Google Scholar | 2 |