| Yazarlar (2) |
Doç. Dr. Hasan Esat YÜCEL
Türkiye |
Doç. Dr. Bilal İLANBEY
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| Objective: Aim of this study is to investigate the correlation of Growth differentiation factor-15 with renal damage and dyslipidemia in Type-2 Diabetes Mellitus.Material and Method: The study was conducted prospectively with patients diagnosed with Type-2 Diabetes Mellitus. Two groups were formed as non-albuminuric (n: 47) and albuminuric (n: 24). Age, gender, Growth differentiation factor-15, glycemic index, lipid panel, glomerular filtration rate, complete blood count, urine albumin/creatin and urine protein/creatin of the groups were compared, and their correlations were examined.Results: Growth differentiation factor-15, age, and hemoglobin A1c were found to be higher in the albuminuric group, and hemoglobin and hematocrit levels were found to be lower. A positive correlation of Growth differentiation factor-15 with spot urine albumin/creatin and protein/creatin was observed in the albuminuric group. In the non-albuminuric group, positive correlation was observed with Triglyceride and a negative correlation with high-density lipoprotein cholesterol. Negative correlation of Growth differentiation factor-15 glomerular filtration rate was detected in all participants.Conclusions: Growth differentiation factor-15 has been found positively associated with albuminuria and high triglyceride levels in Type-2 Diabetes Mellitus. It is negatively correlated with glomerular filtration rate and high-density lipoprotein cholesterol. It is strongly associated with renal damage and dyslipidemia. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Diğer hakemli uluslarası dergilerde yayınlanan tam makale |
| Dergi Adı | Medical Science and Discovery |
| Dergi ISSN | 2148-6832 |
| Dergi Tarandığı Indeksler | Index Copernicus |
| Makale Dili | İngilizce |
| Basım Tarihi | 06-2022 |
| Cilt No | 9 |
| Sayı | 6 |
| Sayfalar | 334 / 339 |
| Doi Numarası | 10.36472/msd.v9i6.746 |
| Makale Linki | http://dx.doi.org/10.36472/msd.v9i6.746 |
| Atıf Sayıları | |
| Google Scholar | 2 |
