| Yazarlar |
Bilal İLANBEY
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Hasan Esat YÜCEL
Türkiye |
Cahit Uçar
Türkiye |
Özkan KOCAMIŞ
Türkiye |
| Özet |
| Aims Increasing evidence has shown that selenoprotein P levels are elevated in type 2 diabetes mellitus and are associated with insulin resistance and release. This study aimed to determine if there was a connection between selenoprotein P levels and metabolic parameters in patients with diabetes with microvascular complications. Methods Serum selenoprotein P concentrations were measured by ELISA in 44 patients with diabetes with complications and 36 patients with diabetes without complications. Results There was no statistically significant difference in selenoprotein P levels between the groups [1.9 (0.9-2.6) and 1.9 (0.8-2.4) ng/mL, respectively, p = 0.565]. Selenoprotein P, glucose, glycosylated hemoglobin, C-reactive protein, triglycerides, total cholesterol, and low-density lipoprotein cholesterol levels were not statistically significantly correlated in patients with complications. However, there was a significant correlation with high-density lipoprotein cholesterol (r = - 0.401, p = 0.042). Conclusions We did not find high selenoprotein P levels in patients with complications, but its inverse association with high-density lipoprotein cholesterol indicates that it may play a role in developing cardiovascular disease in this community of patients. |
| Anahtar Kelimeler |
| Selenoprotein P | Microvascular complications | Diabetic complications | Diabetes mellitus |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | INTERNATIONAL JOURNAL OF DIABETES IN DEVELOPING COUNTRIES |
| Dergi ISSN | 0973-3930 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 10-2022 |
| Cilt No | 42 |
| Sayı | 4 |
| Sayfalar | 735 / 740 |
| Doi Numarası | 10.1007/s13410-021-01029-0 |
| Makale Linki | https://doi.org/10.1007/s13410-021-01029-0 |
| Atıf Sayıları |
