Yazarlar |
Mustafa Nazıroğlu
Süleyman Demirel Üniversitesi, Türkiye |
Cemil Özgül
|
Mustafa Küçükayaz
|
Doç. Dr. Bilal ÇİĞ
Süleyman Demirel Üniversitesi, Türkiye |
Simon Hebeısen
|
Ramazan Bal
|
Özet |
It has been recently reported that the essential antioxidant element selenium has protective effects on cytosolic Ca2+ levels in cell lines. However, the effects of selenium on like transient receptor potential melastatin 2 (TRPM2) in response to oxidative stress (H2O2) are not well understood. We investigated the effects of selenium on H2O2-induced TRPM2 channel currents in the Chinese hamster ovary (CHO) cell line using patch-clamp and fura-2 fluorescence imaging techniques. |
Anahtar Kelimeler |
Makale Türü | Özgün Makale |
Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
Dergi Adı | BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY |
Dergi ISSN | 1742-7835 |
Dergi Tarandığı Indeksler | SCI-Expanded |
Makale Dili | İngilizce |
Basım Tarihi | 02-2013 |
Cilt No | 112 |
Sayı | 2 |
Sayfalar | 96 / 102 |
Doi Numarası | 10.1111/j.1742-7843.2012.00934.x |