Selenium modulates oxidative stress induced TRPM2 cation channel currents in transfectedChinese hamster ovary cells
Yazarlar (6)
Mustafa Nazıroğlu
Süleyman Demirel University, Faculty Of Medicine, Türkiye
Cemil Özgül
Süleyman Demirel University, Faculty Of Medicine, Türkiye
Mustafa Küçükayaz
Süleyman Demirel University, Faculty Of Medicine, Türkiye
Doç. Dr. Bilal ÇİĞ
Süleyman Demirel University, Faculty Of Medicine, Türkiye
Simon Hebeısen
B'sys Gmbh, İsviçre
Ramazan Bal
Firat Üniversitesi Tip Fakültesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Basic and Clinical Pharmacology and Toxicology | ||
| Dergi ISSN | 1742-7835 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 02-2013 |
| Cilt / Sayı / Sayfa | 112 / 2 / 96–102 | DOI | 10.1111/j.1742-7843.2012.00934.x |
| Makale Linki | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1742-7843.2012.00934.x | ||
| Özet |
| It has been recently reported that the essential antioxidant element selenium has protective effects on cytosolic Ca2+ levels in cell lines. However, the effects of selenium on like transient receptor potential melastatin 2 (TRPM2) in response to oxidative stress (H2O2) are not well understood. We investigated the effects of selenium on H2O2-induced TRPM2 channel currents in the Chinese hamster ovary (CHO) cell line using patch-clamp and fura-2 fluorescence imaging techniques. |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 29 |
| SCOPUS | 30 |