First-Time Identification of the PPAT Protein as a Novel Antibacterial Target: Antimicrobial and Antioxidant Insights from E. purpurea
Yazarlar (5)
Prof. Dr. Safiye Elif Korcan Uşak Üniversitesi, Türkiye
Dr. Öğr. Üyesi Nevin Çankaya Uşak Üniversitesi, Türkiye
Prof. Dr. İbrahim Bulduk Afyon Kocatepe Üniversitesi, Türkiye
Prof. Dr. Serap YALÇIN AZARKAN Kırşehir Ahi Evran Üniversitesi, Türkiye
Şah İsmail Çivi
Usak University
Usak University
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | ACS OMEGA (Q2) | ||
| Dergi ISSN | 2470-1343 Dergi Bilgileri (2025) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 05-2025 |
| Cilt / Sayı / Sayfa | 10 / 21 / 21499–21509 | DOI | 10.1021/acsomega.5c00273 |
| Makale Linki | https://doi.org/10.1021/acsomega.5c00273 | ||
| UAK Araştırma Alanları |
Tıbbi Farmakoloji
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| Özet |
| Echinacea purpurea (Asteraceae) is a perennial medicinal herb with immune-stimulating and anti-inflammatory properties. In this study, the antioxidant and antibacterial properties of the organs of the E. purpurea plant were investigated, and significant amounts of total phenolic and total flavonoid contents were detected in flower extracts. It was determined that the DPPH% values of the water extract were higher than the values of methanol extracts. It was observed that Fe3+ reduction capacity increased as the concentration increased in all plant extracts. The highest antimicrobial activity was determined to be against Pseudomonas aeruginosa (35 mm) and Klebsiella pneumonia (20 mm) at the petal (EpP)–methanol extract. In HPLC analysis of component-based phenolic substances, protocatechuic acid, caffeic acid, coumaric acid, chlorogenic acid, and ferulic acid were determined in the extracts. The lowest protein … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 1 |