| Yazarlar (2) |
Doç. Dr. Erdoğan SÖKMEN
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Muhammet Salih ATEŞ
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| Aim: Coronary slow flow (CSF) is an important clinical entity that may cause anginal symptomatology, acute coronary syndrome or even sudden Its pathogenesis is complex, and previously, several hematological parameters were shown to be independently associated with CSF. Platelet mass is a novel platelet index showing bodily inflammation and thrombogenesis status. Our aim was to assess the relationship between PMI and CSF patients undergoing coronary angiography. Material and Methods: Our study is retrospective and a total of 92 patients with CSF and 100 age-and sex-matched subjects with normal coronary included between June 2020 and October 2023. Data regarding demographic, clinical and angiographic characteristics were retrieved from digital database. TIMI frame count (TFC) were calculated by two independent cardiologists blinded to the study protocol. PMI was calculated as multiplied by mean platelet volume (MPV). Results: Mean TFC was (43.93 +/- 9.56 vs 20.0 +/- 4.1, respectively, p<0.001). Respective MPV and PMI of CSF and control groups were 8.64 +/- 0.88 fLvs (p<0.001) and 2983.5 (2692.5-3217.2) vs 2261.5 (2100-2456) (p<0.001). PMI (rho=0.578, p<0.001) and MPV (rho=0.395, p<0.001) were correlated regression analysis, MPV and PMI were independently associated with CSF. In ROC analysis, MPV cut-off was 80.5 fLwith 70% sensitivity and 68% (AUC: 0.755), and PMI cut-off was 2564 with 80% sensitivity and 82% specificity (AUC: 0.866). Discussion: PMI and MPV are increased in CSF, and PMI and MPV are independently associated with CSFP. |
| Anahtar Kelimeler |
| Platelet Mass Index | Coronary Slow Flow Phenomenon | Timi Frame Count | Mean Platelet Volume |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | ESCI dergilerinde yayınlanan tam makale |
| Dergi Adı | ANNALS OF CLINICAL AND ANALYTICAL MEDICINE |
| Dergi ISSN | 2667-663X Wos Dergi |
| Makale Dili | İngilizce |
| Basım Tarihi | 04-2025 |
| Cilt No | 16 |
| Sayı | 4 |
| Sayfalar | 286 / 291 |
| DOI Numarası | 10.4328/ACAM.22423 |
| Atıf Sayıları | |
| WoS | 1 |
