img
img
Efficiency of medical leech on experimentally induced incisional wound healing in rats      
Yazarlar (5)
Dr. Öğr. Üyesi Alican BİLDEN Dr. Öğr. Üyesi Alican BİLDEN
Kırşehir Ahi Evran Üniversitesi, Türkiye
Özlem Kara
Arş. Gör. Merve KAHRAMAN Arş. Gör. Merve KAHRAMAN
Kırşehir Ahi Evran Üniversitesi, Türkiye
Nebahat Çağlayan
Prof. Dr. Muttalip ÇİÇEK Prof. Dr. Muttalip ÇİÇEK
Kırşehir Ahi Evran Üniversitesi, Türkiye
Devamını Göster
Özet
This study was conducted in response to the increasing interest in understanding the effects of both modern and traditional complementary medicine on incisional wound healing. Herein, it was aimed to investigate the wound healing effects of medicinal leech therapy and leech saliva in an experimentally created incisional skin wound model. Fifteen rats underwent full-thickness incisions on their dorsal regions and were randomly assigned to five equal groups, as the Leech Saliva (LS) group, where wounds were treated topically with leech saliva once daily; Leech Therapy-1 (LT-1) group, where leech therapy was administered once at the beginning of the experiment; Leech Therapy-2 (LT-2) group, where leech therapy was applied twice, on days 0 and 3; Positive Control (PC) group, where wounds were treated daily with Phyto cream containing Triticum vulgare; and Negative Control (NC) group, where no treatment was given. Wound healing was assessed daily, and the experiment continued until complete healing was observed. At the conclusion, the wound size, appearance, and histological features were analyzed to compare healing progress across the groups. Medicinal leech therapy was observed to have a positive wound healing effect in the rat model.
Anahtar Kelimeler
in vivo | incisional wound | medicinal leech therapy
Makale Türü Özgün Makale
Makale Alt Türü SCOPUS dergilerinde yayımlanan tam makale
Dergi Adı Journal of Complementary and Integrative Medicine
Dergi ISSN 2194-6329 Scopus Dergi
Dergi Tarandığı Indeksler Scopus
Makale Dili İngilizce
Basım Tarihi 02-2025
Sayı 1
Doi Numarası 10.1515/jcim-2024-0351
Makale Linki https://doi.org/10.1515/jcim-2024-0351