Is there a risk of developmental problems in infants born to mothers with gestational diabetes mellitus and/or pre-eclampsia?
 
Yazarlar (8)
Dr. Öğr. Üyesi Yusuf TOPAL Kırşehir Ahi Evran Üniversitesi, Türkiye
Esra Kınacı Biber Düzce Üniversitesi, Türkiye
Zeynep Arıkan Karamanoğlu Mehmetbey Üniversitesi, Türkiye
Dr. Öğr. Üyesi Gülsen Sırtbaş Van Yüzüncü Yıl Üniversitesi, Türkiye
Doğan Porsnok Bingöl Üniversitesi, Türkiye
Hasan Tolga Çelik Hacettepe Üniversitesi, Türkiye
Prof. Dr. Akmer Mutlu Hacettepe Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Plos One (Q2)
Dergi ISSN 1932-6203 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2025
Cilt / Sayı / Sayfa 20 / 1 / – DOI 10.1371/journal.pone.0318003
Makale Linki https://doi.org/10.1371/journal.pone.0318003
UAK Araştırma Alanları
Fizyoterapi ve Rehabilitasyon
Özet
Objective The aims of this study were (i) to describe the early spontaneous movements in 3-to 5-month-old infants in groups of infants born to mothers with GDM and/or PE, (ii) to compare them, and (iii) to analyze the differences between infants with these risk factors and typically developing infants born to mothers without GDM and/or PE and other risk factors. Methods This cohort study included 255 infants in 4 groups: (i) 96 infants born to mothers with GDM, (ii) 78 infants born to mothers with PE, (iii) 31 infants born to mothers with GDM and PE, and (iv) 50 typically developing infants. Early spontaneous movements, including not only fidgety movements but also concurrent movement and postural patterns, were assessed using the General Movements Assessment (GMA), which determines the Motor Optimality Score-Revised (MOS-R). Comparisons were made using one-way ANOVA for normally distributed continuous variables, Kruskal-Wallis test for non-normally distributed data, and Pearson chi-squared for categorical variables. Univariate logistic regression analyses were used to determine the odds ratios (OR) with 95% confidence intervals (CI). Results There were no differences between the three groups, which included infants whose mothers had at least one of these risk factors (p>0.05). Infants born to mothers with GDM, infants born to mothers with PE, and infants born to mothers with both GDM and PE had more aberrant fidgety movements, reduced age-adequate movement repertoire, and more abnormal postural patterns than typically developing infants (p<0.05), in addition to lower MOS-R. When looking at those with ≤24 in MOS …
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Is there a risk of developmental problems in infants born to mothers with gestational diabetes mellitus and/or pre-eclampsia?

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