No Association Between Serum Paraoxonase, Arylesterase Activities, and Hydatidiform Mole
Yazarlar (8)
Ebru Ozturk
Gaziantep University, Türkiye
Ozcan Balat
Gaziantep University, Türkiye
Ebru Dikensoy
Gaziantep University, Türkiye
Mete Gurol Ugur
Gaziantep University, Türkiye
Caglayan Ozcan
Gaziantep University, Türkiye
Prof. Dr. Abdullah AYDIN
Kırşehir Ahi Evran Üniversitesi, Türkiye
Ozcan Erel
Ankara Etlik Ihtisas Egitim ve Arastirma Hastanesi, Türkiye
Seval Kul
Gaziantep University, Türkiye
| Makale Türü | Özgün Makale (ESCI dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER | ||
| Dergi ISSN | 1048-891X Wos Dergi Scopus Dergi | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2011 |
| Cilt / Sayı / Sayfa | 21 / 1 / 149–152 | DOI | 10.1097/IGC.0b013e3182021c59 |
| Özet |
| In this study, we aimed to evaluate the association between hydatidiform mole (HM) and paraoxonase 1 (PON1) activity and phenotyping in comparison with healthy subjects (both pregnant and nonpregnant women). Eighty women were enrolled in this study. Of these, 26 had HM (group 1). Twenty-seven healthy women in the first trimester of pregnancy with a single viable fetus were included in the study as control subjects (group 2). The remaining 27 subjects were healthy nonpregnant women who also participated as control subjects (group 3). Paraoxonase and arylesterase activities were measured using commercially available kits (Relassay, Gaziantep, Turkey). Paraoxonase activity measurements were performed both in the absence (basal activity) and presence of NaCl (salt-stimulated activity). The phenotype distribution of PON1 activity was determined by the double-substrate method. Basal and salt-stimulated paraoxonase and arylesterase activities were not significantly different between the HM, healthy pregnant control, and healthy nonpregnant control groups. Hence, PON1 phenotype distribution of the subjects was not significantly different between these 3 groups. We determined no association between HM (complete or partial) and PON1 activity and phenotyping in comparison with pregnant and nonpregnant healthy subjects. Further studies including metastatic or invasive HM are needed. |
| Anahtar Kelimeler |
| Paraoxonase | Arylesterase | Hydatidiform mole |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları |