| Yazarlar (11) |
Sidika Seyma Ozkanli
|
|
Itir Ebru Zemheri
|
|
Asif Yildirim
|
|
Hatice Deniz Gur
|
|
Mevlana Derya Balbay
|
|
Serkan Senol
|
|
Ahmet Oguz Ozkanli
|
|
Erdal Alkan
|
|
Tulay Zenginkinet
|
Prof. Dr. Abdullah AYDIN
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Turhan Caskurlu
|
| Özet |
| To evaluate the relation between biochemical recurrence (BCR) of prostate cancer and the extent of positive surgical margins (PSMs), Gleason score (GS) of the tumor at the margins, and preoperative prostate-specific antigen (PSA) levels. A total of 94 patients who underwent radical prostatectomy were recruited for this study and received postoperative follow-up care for 2 years. All specimens were evaluated for surgical margin status, PSM length, GS at positive margin, size of tumor, multifocality, invasion of seminal vesicle, lymphovascular invasion, and perineural invasion. PSM was defined as a prostate tumor. Out of 94 patients, 34 patients (36.2%) had PSMs and 46 patients (48.9%) had BCR. A statistically significant relation between having a high risk of BCR of prostate cancer and having high preoperative PSA levels (P < 0.001), PSMs (P < 0.001), or a high GS at the surgical margin (P = 0.024) was found. High preoperative PSA levels, PSMs, and tumors with high GS at the margins have a poor prognostic impact, and they correlate with a higher rate of BCR. Close follow-up of patients with PSMs with high GS and high levels of preoperative PSA is recommended. |
| Anahtar Kelimeler |
| Prostate cancer | surgical margin | biochemical recurrence |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | ESCI dergilerinde yayımlanan tam makale |
| Dergi Adı | TURKISH JOURNAL OF MEDICAL SCIENCES |
| Dergi ISSN | 1300-0144 Wos Dergi Scopus Dergi |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2014 |
| Cilt No | 44 |
| Sayı | 3 |
| Sayfalar | 397 / 403 |
| Doi Numarası | 10.3906/sag-1303-128 |
| Atıf Sayıları | |
| WoS | 8 |
