Synchronous Endometrial and Ovarian Cancer With Sigmoid Colon Metastasis One Year After Primary Surgery: A Case Report
Yazarlar (7)
Kadir Guzin Istanbul Goztepe Training & Research Hospital, Türkiye
Burcin Karamustafaoglu Balci Istanbul Goztepe Training & Research Hospital, Türkiye
Kemal Sandal Istanbul Goztepe Training & Research Hospital, Türkiye
Ahmet Gocmen Istanbul Goztepe Training & Research Hospital, Türkiye
Ozgur Ekinci Istanbul Medeniyet University, Türkiye
Prof. Dr. Abdullah AYDIN Kırşehir Ahi Evran Üniversitesi, Türkiye
Meryem Yuvruk Istanbul Medeniyet University, Türkiye
Makale Türü Açık Erişim Özgün Makale (ESCI dergilerinde yayınlanan tam makale)
Dergi Adı INTERNATIONAL JOURNAL OF WOMENS HEALTH AND REPRODUCTION SCIENCES
Dergi ISSN 2330-4456 Wos Dergi Scopus Dergi
Makale Dili İngilizce Basım Tarihi 10-2015
Cilt / Sayı / Sayfa 3 / 4 / 220–222 DOI 10.15296/ijwhr.2015.46
Makale Linki https://ijwhr.net/pdf.php?id=130
Özet
Introduction: We describe a patient who had ovarian and endometrial cancer which metastasized to sigmoid colon one year after surgery.
Case Presentation: A 53-year-old woman was admitted with the complaints of abdominal pain, abdominal distension and postmenopausal bleeding. Her transvaginal ultrasound scan revealed a cystic mass containing papillary projections with the dimensions of 6.5 x 5 x 4 cm on the right ovary. Level of (carbohydrate antigen) (CA) 125 was 223 IU. Dilation and curettage revealed endometrioid adenocarcinoma. Debulking surgerywas carried out. Histopathological diagnosis was grade 2 adenocarcinoma with squamous differentiation for endometrial cancer and grade 2 endometrioid adenocarcinoma with squamous and mucinous differentiation for ovarian cancer. The stage was 1A for endometrial cancer and 1A for ovarian cancer. 12 months after the operation CA 125 level was 112 IU. Positron emission tomography (PET) scan showed a small lesion (1.5x1.5 cm) in the pelvic cavity with increased fluorodeoxyglucose (FDG) uptake. Five months after the chemotherapy, CA 125 level elevated from 10 to 60 IU and subsequent magnetic resonance imaging (MRI) revealed a tumoral mass with the dimensions of 3x2.2 cm. A second laparotomy was performed and the metastasis was excited. The tumor was endometrioid adenocarcinoma with infiltration in the serosa and muscularis propria of sigmoid colon.
Conclusion: It is needed to consider the possibility of double cancer in the diagnosis and treatment of gynecological malignancies.
Anahtar Kelimeler
Endometrial neoplasms | Neoplasm metastasis | Ovarian neoplasms | CA-125 antigen