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Platelet-albumin-bilirubin score and systemic immune-inflammation index for assessing the prognosis of acute ischemic stroke patients  
Yazarlar (7)
Dr. Öğr. Üyesi Selcen DURAN Dr. Öğr. Üyesi Selcen DURAN
Kırşehir Ahi Evran Üniversitesi, Türkiye
Asuman ÇELİKBİLEK
Kırşehir Ahi Evran Üniversitesi, Türkiye
Dr. Öğr. Üyesi Aysu YETİŞ Dr. Öğr. Üyesi Aysu YETİŞ
Kırşehir Ahi Evran Üniversitesi, Türkiye
Dr. Öğr. Üyesi Burç Esra ŞAHİN Dr. Öğr. Üyesi Burç Esra ŞAHİN
Kırşehir Ahi Evran Üniversitesi, Türkiye
Dr. Öğr. Üyesi Aydan KÖYSÜREN Dr. Öğr. Üyesi Aydan KÖYSÜREN
Kırşehir Ahi Evran Üniversitesi, Türkiye
Prof. Dr. Memiş BOLACALI Prof. Dr. Memiş BOLACALI
Kırşehir Ahi Evran Üniversitesi, Türkiye
Bekircan Polat
Kırşehir Ahi Evran Üniversitesi, Turkey
Devamını Göster
Özet
Objectives: This study investigated the prognostic value of the systemic immune-inf lammation index (SII) and platelet-albumin-bilirubin (PALBI) score in patients with acute ischemic stroke (AIS). Patients and methods: A total of 211 patients (120 males, 91 females; mean age: 70.9±13.2 years; range, 25 to 98 years) with AIS and 145 controls (72 males, 73 females; mean age: 69.4±8.4 years; range, 53 to 88 years) were included in this prospective study between March 2023 and December 2023. Demographic data and laboratory results upon admission were recorded. The SII and PALBI scores were calculated from laboratory parameters. Results: The SII was significantly higher in the stroke group compared to controls (p<0.001), while PALBI scores were similar between the groups (p=0.169). According to the TOAST (Trial of ORG 10172 in Acute Stroke Treatment) classification, SII was comparable across the subgroups (p=0.964), but PALBI scores were significantly higher in the cardioembolic group (p=0.002). In terms of stroke severity, SII showed no significant differences between subgroups (p=0.701); however, patients with moderate-to-severe stroke had significantly higher PALBI scores than those with minor stroke (p=0.008). Both SII (p=0.007) and PALBI scores (p=0.019) were significantly elevated in AIS patients with stroke-related complications. Conclusion: A higher PALBI score was associated with stroke severity, and both PALBI and SII values were elevated in AIS patients with complications, indicating a poor prognosis.
Anahtar Kelimeler
Acute ischemic stroke | platelet-albumin-bilirubin | prognosis | stroke severity | systemic immune-inflammation index
Makale Türü Özgün Makale
Makale Alt Türü ESCI dergilerinde yayımlanan tam makale
Dergi Adı Turk Noroloji Dergisi
Dergi ISSN 1301-062X
Makale Dili İngilizce
Basım Tarihi 01-2025
Cilt No 31
Sayı 1
Sayfalar 34 / 40
Doi Numarası 10.55697/tnd.2025.232