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Effects of pyrolytic carbon on postoperative adhesion formation in rats   
Yazarlar (7)
Suzi Demirbag
Cuneyt Atabek
Ahmet Guven
Emin Oztas
Ilhami Surer
Prof. Dr. Hülya ÖZTÜRK Prof. Dr. Hülya ÖZTÜRK
Kırşehir Ahi Evran Üniversitesi, Türkiye
Narter Yesildaglar
Devamını Göster
Özet
Peritoneal adhesion is a consequence of wound healing that sometimes causes severe postoperative complications. Despite all the preventive measures and agents, adhesions have still not been eliminated completely. The aim of this study was to evaluate the effects of pyrolytic carbon on the development of postoperative peritoneal and uterine tube adhesions. Twenty female Wistar-Albino type rats were used in this study. The rats were divided into two groups: treatment and control groups. After ketamine anaesthesia (50 mg/kg IM), a lower midline abdominal incision was performed and a standard uterine lesion was created by electrocauterization. In the study group, pyrolytic carbon was applied to the surface of the uterus and no additional procedure was applied in the control group. After 2 weeks, all of the rats were killed and uterine adhesions were staged according to the Leach scoring system. In the control group, the total adhesion score was 8.8 +/- 0.42. In the study group, the total adhesion score was 3.3 +/- 1.49, significantly lower than that in the control group (P < 0.001). Pyrolytic carbon significantly reduces the prevalence of peritoneal and uterine tube adhesion formation in rats. However, further more detailed investigations are needed before this material is used in clinical practice.
Anahtar Kelimeler
Adhesion formation | Pyrolytic carbon | Treatment | Rats
Makale Türü Özgün Makale
Makale Alt Türü ESCI dergilerinde yayımlanan tam makale
Dergi Adı ARCHIVES OF GYNECOLOGY AND OBSTETRICS
Dergi ISSN 0932-0067 Wos Dergi Scopus Dergi
Makale Dili İngilizce
Basım Tarihi 01-2009
Cilt No 279
Sayı 1
Sayfalar 11 / 15
Doi Numarası 10.1007/s00404-008-0649-9
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 1
Effects of pyrolytic carbon on postoperative adhesion formation in rats

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