| Yazarlar (5) |
Dr. Öğr. Üyesi Aysu YETİŞ
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Asuman ÇELİKBİLEK
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Doç. Dr. Bilal İLANBEY
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Naime Meric Konar
|
Dr. Öğr. Üyesi Selcen DURAN
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| Neurofilament light chain (NfL) has emerged as a promising biomarker for several neurological diseases. Therefore, we investigated its serum levels and their association with disease characteristics, including duration, severity, and medication use in patients with restless legs syndrome (RLS). This cross-sectional prospective study included 71 RLS patients and 70 healthy controls. RLS patients were characterized based on disease duration, severity, and medication use. NfL levels were quantified using commercial enzyme-linked immunosorbent assay kits. No significant differences in NfL levels were observed between RLS patients and controls ( > 0.05). Furthermore, the levels were not significantly associated with disease duration or severity in RLS patients ( > 0.05). These findings do not support the use of NfL as a biomarker for RLS. Further large-scale studies are needed to evaluate its role in RLS. |
| Anahtar Kelimeler |
| Neurofilament light chain | restless legs syndrome | neurodegeneration | Willis-Ekbom disease | biomarker |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | ESCI dergilerinde yayımlanan tam makale |
| Dergi Adı | NEUROLOGICAL RESEARCH |
| Dergi ISSN | 0161-6412 Wos Dergi Scopus Dergi |
| Makale Dili | İngilizce |
| Basım Tarihi | 03-2025 |
| Doi Numarası | 10.1080/01616412.2025.2472836 |
| Atıf Sayıları |
