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Synthesis of Novel Schiff Bases with Piperidine Rings and Investigation of Their Antioxidant Capacities and Anticholinesterase and Carbonic Anhydrase Enzyme Inhibition Properties   
Yazarlar (1)
Dr. Öğr. Üyesi Sertan AYTAÇ Dr. Öğr. Üyesi Sertan AYTAÇ
Kırşehir Ahi Evran Üniversitesi, Türkiye
Devamını Göster
Özet
The use of Schiff bases especially in chemistry, medicine, pharmacy, and various industries has increased the importance of these compounds. Schiff bases and their derivatives show important bioactive properties in a wide range. Compounds containing phenol and its derivatives in their molecular structures have the potential to capture free radicals associated with various diseases. In this study, five new Schiff bases (13–17) having piperidine rings containing phenol groups, which have the potential to be used as antioxidants, were synthesized for the first time using microwave energy. The antioxidant effects of the compounds used in the syntheses (7–12) and the obtained new Schiff bases (13–17) and their inhibitory abilities against some metabolic enzymes including acetylcholinesterase (AChE) and human carbonic anhydrases I and II (hCAs I and hCAs II) were determined. In addition to the experimental …
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı ChemistrySelect
Dergi ISSN 2365-6549 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q3
Makale Dili Türkçe
Basım Tarihi 04-2025
Cilt No 10
Sayı 13
Doi Numarası 10.1002/slct.202500365
Makale Linki https://doi.org/10.1002/slct.202500365