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Investigation of the Electrochemical Behavior of the Drug Active Ingredient Pirfenidone and Its Analytical Application in Natural Samples   
Yazarlar (5)
Nuray Kökener
Barkın Tunay
Ersin Demir
Afyonkarahisar Sağlık Bilimleri Üniversitesi, Türkiye
Nida Aydoğdu Özdoğan
Afyonkarahisar Sağlık Bilimleri Üniversitesi, Türkiye
Dr. Öğr. Üyesi Murat MISIR Dr. Öğr. Üyesi Murat MISIR
Kırşehir Ahi Evran Üniversitesi, Türkiye
Devamını Göster
Özet
Pirfenidone is an active pharmaceutical ingredient used orally in the treatment of idiopathic pulmonary fibrosis and possesses antifibrotic, antioxidant, and anti-inflammatory properties. Studies conducted on both animals and humans have observed that pirfenidone halts the progression of fibrosis, stabilizes lung function, and reduces the number of acute exacerbations in IPF patients. However, the drug is also associated with side effects such as elevated liver enzymes, liver damage, gastrointestinal problems, photosensitivity reactions, and rashes. Therefore, monitoring liver function during treatment is essential.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü Diğer hakemli uluslarası dergilerde yayımlanan tam makale
Dergi Adı International Bulletin of Electrochemical Methodology
Dergi ISSN 3062-1496
Dergi Tarandığı Indeksler
Makale Dili İngilizce
Basım Tarihi 12-2024
Cilt No 1
Sayı 1
Doi Numarası 10.5281/zenodo.14568814
Makale Linki https://doi.org/10.5281/zenodo.14568814