| Yazarlar |
Prof. Dr. Belgin ERDEM
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Eyüp Bağcı
Fırat Üniversitesi, Türkiye |
|
Gülden Doğan
Fırat Üniversitesi, Türkiye |
|
Ekrem Aktoklu
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Alpaslan Dayangaç
Osmaniye Korkut Ata Üniversitesi, Türkiye |
| Özet |
| Purpose: To investigate the chemical composition of the essential oil of Cyperus fuscus burs as well as the antimicrobial activities of the ethanol extracts and essential oil. Methods: Fresh burs roots of C. fuscus were collected at the flowering stage in an open area in Güdül (Ankara, Turkey). Preparation of the ethanol extract, hydrodistillation of the essential oil, GC-FID-MS analysis, and agar diffusion and MIC agar dilution assays were performed to determine various parameters for the oil and extracts. Results: The major compounds of the essential oil were dehydroaromadendrene (10.7 %), azulenone (8.5 %), α-selinene (7.5 %), α-ylangene (6.0 %) and β-caryophyllene (5.6 %). The essential oil of Cyperus fuscus exhibited activity against Gram-negative bacteria with minimum ınhibitory concentration (MIC) values ranging from 1000 to 31.25 μl/mL. Similarly, the ethanol extract of the burs showed good antimicrobial activity with the MIC of the ethanol extracts on ranging from 1000 μg/mL (Escherichia coli) to 250 µg/mL (Pseudomonas. Aeruginosa, p < 0.05). However, the ethanol extract was inactive against yeast strains. Conclusion: Thus, the essential oil and ethanol extract of the studied plant can potentially be used as antimicrobial agent. |
| Anahtar Kelimeler |
| Antimicrobial activity | Chemical composition | Cyperus fuscus | Essential oil |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH |
| Dergi ISSN | 1596-5996 |
| Dergi Tarandığı Indeksler | SCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2018 |
| Cilt No | 17 |
| Sayı | 8 |
| Sayfalar | 1637 / 1643 |
| Doi Numarası | 10.4314/tjpr.v17i8.24 |
| Atıf Sayıları | |
| SCOPUS | 6 |
