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Protective effects of turmeric (Curcuma longa L.) supplementation on oxidative stress and metabolic parameters in rats with high-fructose diet-induced metabolic syndrome      
Yazarlar (7)
Dr. Öğr. Üyesi Kübra ÖZTÜRK Dr. Öğr. Üyesi Kübra ÖZTÜRK
Kırşehir Ahi Evran Üniversitesi, Türkiye
Gonca Ozan Kocamüftüoğlu
Burdur Mehmet Akif Ersoy Üniversitesi, Türkiye
Mustafa Karatepe
Fırat Üniversitesi, Türkiye
Mehmet Ali Kısaçam
Türkiye
Nalan Kaya Tektemur
Fırat Üniversitesi, Türkiye
Elif Onat
Adıyaman Üniversitesi, Türkiye
İbrahim Enver Ozan
Türkiye
Devamını Göster
Özet
BackgroundMetabolic syndrome (MetS) is a growing global health concern characterized by oxidative stress and metabolic dysregulation. Identifying natural compounds with therapeutic potential to mitigate these effects is essential. Antioxidant parameters are crucial in reducing oxidative stress, which is a key factor in the pathophysiology of MetS.ObjectiveThis study aimed to evaluate the protective effects of turmeric (Curcuma longa L.) supplementation on oxidative stress markers, biochemical parameters, and histological outcomes in a rat model of MetS induced by a high-sugar diet.MethodsFemale Sprague--Dawley rats (n= 32) were divided into four groups: Control, metabolic syndrome (MetS--20% fructose), turmeric (80 mg/kg/day), and MetS+ turmeric (80 mg/kg/day). Turmeric was administered orally for 60 days. Oxidative stress markers, lipid profiles, glucose levels, and histological changes were analyzed to ...
Anahtar Kelimeler
Curcuma Longa L. (Turmeric) | Liver | Metabolic syndrome | Oxidative stress | Vitamins
Makale Türü Özgün Makale
Makale Alt Türü ESCI dergilerinde yayımlanan tam makale
Dergi Adı Nutrire
Dergi ISSN 2316-7874
Dergi Tarandığı Indeksler ESCI
Makale Dili İngilizce
Basım Tarihi 02-2025
Cilt No 50
Sayı 10
Sayfalar 1 / 13
Doi Numarası 10.1186/s41110-025-00316-8
Makale Linki https://doi.org/10.1186/s41110-025-00316-8